Plasmodium spp. is the etiological agent of malaria, a life-threatening parasitic disease
transmitted by infected mosquitoes. Malaria remains a major global health challenge …

Throughout the last decades, mRNA vaccines have been developed as a cancer
immunotherapeutic and the technology recently gained momentum during the COVID-19 …

The liver's unique characteristics have a profound impact on the priming and maintenance of
adaptive immunity. This review delves into the cellular circuits that regulate adaptive …

Malaria, caused by Plasmodium species, remains a major global health concern, causing
millions of deaths annually. While the introduction of the RTS, S vaccine has shown promise …

Adjuvanticity and delivery are crucial facets of mRNA vaccine design. In modern mRNA
vaccines, adjuvant functions are integrated into mRNA vaccine nanoparticles, allowing the …

Adjuvants play pivotal roles in vaccine development, enhancing immunization efficacy
through prolonged retention and sustained release of antigen, lymph node targeting, and …

Although various types of mRNA-based vaccines have been explored, the optimal
conditions for induction of both humoral and cellular immunity remain rather unknown. In this …

Mucosal-associated invariant T (MAIT) cells are an unconventional T cell population that are
highly abundant in humans. They possess a semi-invariant T cell receptor (TCR) that …

Malaria vaccine introduction in endemic countries is a game-changing milestone in the fight
against the disease. This article examines the inequity in the global pharmaceutical …

Attenuated sporozoites provide a valuable model for exploring protective immunity against
the malarial liver stage, guiding the design of highly efficient vaccines to prevent malaria …