[HTML][HTML] Analytical performance characteristics of the Cepheid GeneXpert Ebola assay for the detection of Ebola virus

BA Pinsky, MK Sahoo, J Sandlund, M Kleman… - PloS one, 2015 - journals.plos.org
Background The recently developed Xpert® Ebola Assay is a novel nucleic acid
amplification test for simplified detection of Ebola virus (EBOV) in whole blood and buccal …

Development of mobile laboratory for viral hemorrhagic fever detection in Africa

M Weidmann, O Faye, O Faye… - The Journal of …, 2018 - academic.oup.com
Background A mobile laboratory transportable on commercial flights was developed to
enable local response to viral hemorrhagic fever outbreaks. Methods The development …

Lateral flow immunoassays for Ebola virus disease detection in Liberia

JC Phan, J Pettitt, JS George… - The Journal of …, 2016 - academic.oup.com
Abstract Background. Lateral flow immunoassays (LFIs) are point-of-care diagnostic assays
that are designed for single use outside a formal laboratory, with in-home pregnancy tests …

Comparative evaluation of the diagnostic performance of the prototype Cepheid GeneXpert Ebola assay

P Jansen van Vuren, A Grobbelaar… - Journal of clinical …, 2016 - Am Soc Microbiol
The Ebola virus disease (EVD) outbreak in West Africa has highlighted an urgent need for
point-of-care (POC) assays for the diagnosis of this devastating disease in resource-limited …

[HTML][HTML] Validation of use of the miniPCR thermocycler for Ebola and Zika virus detection

E González-González, JL Mendoza-Ramos… - PLoS …, 2019 - journals.plos.org
The development of point-of-care (POC) diagnostic systems has received well-deserved
attention in recent years in the scientific literature, and many experimental systems show …

Rapid optical cavity PCR

JH Son, SG Hong, AJ Haack… - Advanced …, 2016 - Wiley Online Library
Recent outbreaks of deadly infectious diseases, such as Ebola and Middle East respiratory
syndrome coronavirus, have motivated the research for accurate, rapid diagnostics that can …

[HTML][HTML] Challenges and opportunities of centrifugal microfluidics for extreme point-of-care testing

IJ Michael, TH Kim, V Sunkara, YK Cho - Micromachines, 2016 - mdpi.com
The advantages offered by centrifugal microfluidic systems have encouraged its rapid
adaptation in the fields of in vitro diagnostics, clinical chemistry, immunoassays, and nucleic …

[HTML][HTML] Development and evaluation of a rapid and sensitive EBOV-RPA test for rapid diagnosis of Ebola virus disease

M Yang, Y Ke, X Wang, H Ren, W Liu, H Lu, W Zhang… - Scientific reports, 2016 - nature.com
Confirming Ebola virus disease (EVD), a deadly infectious disease, requires real-time RT-
PCR, which takes up to a few hours to yield results. Therefore, a rapid diagnostic assay is …

[HTML][HTML] Comparative performance study of three Ebola rapid diagnostic tests in Guinea

Z Moran, W Rodriguez, D Ahmadou, B Soropogui… - BMC Infectious …, 2020 - Springer
Abstract Background The 2014/15 Ebola outbreak in West Africa resulted in 11,000 deaths
and massive strain on local health systems, and the ongoing outbreak in Democratic …

Evaluation of RealStar reverse transcription–polymerase chain reaction kits for filovirus detection in the laboratory and field

T Rieger, R Kerber, H El Halas… - The Journal of …, 2016 - academic.oup.com
Abstract Background. Diagnosis of Ebola virus (EBOV) disease (EVD) requires laboratory
testing. Methods. The RealStar Filovirus Screen reverse transcription–polymerase chain …