[HTML][HTML] Remdesivir: a review in COVID-19

HA Blair - Drugs, 2023 - Springer
Remdesivir (Veklury®), a nucleotide analogue prodrug with broad-spectrum antiviral activity,
is approved for the treatment of coronavirus disease 2019 (COVID-19), the illness caused by …

Approach to COVID-19 in older adults and indications for improving the outcomes

C Tana, L Moffa, K Falasca, J Vecchiet, M Tana… - Annals of …, 2023 - Taylor & Francis
Background: COVID-19 continues to present challenges in the care of older adults with
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …

Remdesivir reduced mortality in immunocompromised patients hospitalized for COVID-19 across variant waves: findings from routine clinical practice

E Mozaffari, A Chandak, RL Gottlieb… - Clinical Infectious …, 2023 - academic.oup.com
Background Immunocompromised patients are at high risk of severe coronavirus disease
2019 (COVID-19) and death, yet treatment strategies for immunocompromised patients …

[HTML][HTML] Remdesivir Use in the Real-World Setting: An Overview of Available Evidence

K Akinosoglou, EA Rigopoulos, G Schinas, G Kaiafa… - Viruses, 2023 - mdpi.com
In the years of Coronavirus Disease 2019 (COVID-19), various treatment options have been
utilized. COVID-19 continues to circulate in the global population, and the evolution of the …

[HTML][HTML] HIV and COVID-19 Co-Infection: Epidemiology, Clinical Characteristics, and Treatment

D Basoulis, E Mastrogianni, PM Voutsinas… - Viruses, 2023 - mdpi.com
The COVID-19 pandemic has been a global medical emergency with a significant socio-
economic impact. People with HIV (PWH), due to the underlying immunosuppression and …

[HTML][HTML] Effect of remdesivir on mortality and the need for mechanical ventilation among hospitalized patients with COVID-19: real-world data from a resource-limited …

R Metchurtchlishvili, N Chkhartishvili, A Abutidze… - International Journal of …, 2023 - Elsevier
Objectives Georgia introduced remdesivir for the treatment of COVID-19 in December 2020.
We evaluated the real-world effect of remdesivir on mortality and the need for mechanical …

EpiMed Coronabank Chemical Collection: Compound selection, ADMET analysis, and utilisation in the context of potential SARS-CoV-2 antivirals

E Pitsillou, RC Beh, JJ Liang, TS Tang, X Zhou… - Journal of Molecular …, 2023 - Elsevier
Antiviral drugs are important for the coronavirus disease 2019 (COVID-19) response, as
vaccines and antibodies may have reduced efficacy against severe acute respiratory …

[HTML][HTML] Remdesivir Treatment Lacks the Effect on Mortality Reduction in Hospitalized Adult COVID-19 Patients Who Required High-Flow Supplemental Oxygen or …

C Huang, TL Lu, L Lin - Medicina, 2023 - mdpi.com
Background and Objectives: The therapeutic impact of remdesivir on hospitalized adult
COVID-19 patients is unknown. The purpose of this meta-analysis was to compare the …

Remdesivir is associated with reduced mortality in COVID-19 patients requiring supplemental oxygen including invasive mechanical ventilation across SARS-CoV-2 …

E Mozaffari, A Chandak, RL Gottlieb… - Open Forum …, 2023 - academic.oup.com
Background This comparative effectiveness study investigated the effect of remdesivir on in-
hospital mortality among patients hospitalized for coronavirus disease 2019 (COVID-19) …

Executive summary of the consensus statement of the group for the study of infection in transplantation and other immunocompromised host (GESITRA-IC) of the …

S Herrera, JM Aguado, FJ Candel, E Cordero… - Transplantation …, 2023 - Elsevier
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) arose in December 2019
in China rapidly evolving to the Coronavirus Disease 2019 (COVID-19) pandemic. Since …