Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

Several different reactive oxygen species (ROS) are generated in vivo. They have roles in
the development of certain human diseases whilst also performing physiological functions …

Defective antioxidant system as well as mitochondrial dysfunction contributes to the
pathogenesis and progression of diabetic kidney disease (DKD). Nuclear factor erythroid 2 …

The kidney is a crucial organ that eliminates metabolic waste and reabsorbs nutritious
elements. It also participates in the regulation of blood pressure, maintenance of electrolyte …

Nephropathy is the most prevalent microvascular disorder in diabetes mellitus. Oxidative
stress and inflammatory cascade provoked by the persistent hyperglycemic milieu play …

Diabetic kidney disease (DKD) is a major diabetic complication and global health concern,
occurring in nearly 30% to 40% of people with diabetes. Importantly, several therapeutic …

Diabetes mellitus (DM) belongs to the category of socially significant diseases with epidemic
rates of increases in prevalence. Diabetic nephropathy (DN) is a specific kind of kidney …

Oxidative stress and inflammation play a pivotal role in the pathogenesis of diabetic
nephropathy (DN). Local renin-angiotensin systems (RAS) contribute to the pathogenesis …

Reactive oxygen species (ROS) are produced mainly by mitochondrial respiration and
function as signaling molecules in the physiological range. However, ROS production is also …

Simple Summary Allograft inflammatory factor 1 (AIF1) is a calcium-binding protein that
participates in intracellular processes such as phagocytosis, membrane ruffling and F-actin …