[HTML][HTML] The role of macrophages polarization in sepsis-induced acute lung injury

Z Wang, Z Wang - Frontiers in immunology, 2023 - frontiersin.org
Sepsis presents as a severe infectious disease frequently documented in clinical settings.
Characterized by its systemic inflammatory response syndrome, sepsis has the potential to …

[HTML][HTML] Cigarette smoke-induced respiratory response: insights into cellular processes and biomarkers

SR Cha, J Jang, SM Park, SM Ryu, SJ Cho, SR Yang - Antioxidants, 2023 - mdpi.com
Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

The impact of the immune system on lung injury and regeneration in COPD

TS Kapellos, TM Conlon, AÖ Yildirim… - European Respiratory …, 2023 - Eur Respiratory Soc
COPD is a devastating respiratory condition that manifests via persistent inflammation,
emphysema development and small airway remodelling. Lung regeneration is defined as …

Mannosylated polydopamine nanoparticles alleviate radiation-induced pulmonary fibrosis by targeting M2 macrophages and inhibiting the TGF-β1/Smad3 signaling …

L Shen, S Fu, Y Chen, W Li, S Liu, Z Li, J Li, Y Li… - Colloids and Surfaces B …, 2023 - Elsevier
Radiation-induced pulmonary fibrosis (RIPF), one type of pulmonary interstitial diseases, is
frequently observed following radiation therapy for chest cancer or accidental radiation …

Sinensetin Attenuated Macrophagic NLRP3 Inflammasomes Formation via SIRT1-NRF2 Signaling

L Lin, K Deng, Z Gong, H Fan, D Zhang, G Lu - ACS omega, 2023 - ACS Publications
Macrophage-mediated inflammation plays essential roles in multiple-organ injury.
Sinensetin (SNS) at least exhibits anti-inflammation, antioxidant, and antitumor properties …

[HTML][HTML] Mesenchymal stromal cell therapy in lung transplantation

AI Nykänen, M Liu, S Keshavjee - Bioengineering, 2023 - mdpi.com
Lung transplantation is often the only viable treatment option for a patient with end-stage
lung disease. Lung transplant results have improved substantially over time, but ischemia …

[HTML][HTML] MSCs alleviate LPS-induced acute lung injury by inhibiting the proinflammatory function of macrophages in mouse lung organoid–macrophage model

J Zhu, J Zhou, B Feng, Q Pan, J Yang, G Lang… - Cellular and Molecular …, 2024 - Springer
Acute lung injury (ALI) is an inflammatory disease associated with alveolar injury,
subsequent macrophage activation, inflammatory cell infiltration, and cytokine production …

[HTML][HTML] The Plastic Interplay between Lung Regeneration Phenomena and Fibrotic Evolution: Current Challenges and Novel Therapeutic Perspectives

S Lettieri, FR Bertuccio, L Del Frate, F Perrotta… - International Journal of …, 2023 - mdpi.com
Interstitial lung diseases (ILDs) are a heterogeneous group of pulmonary disorders
characterized by variable degrees of inflammation, interstitial thickening, and fibrosis …

[HTML][HTML] Multiomics reveal human umbilical cord mesenchymal stem cells improving acute lung injury via the lung-gut axis

L Lv, EH Cui, B Wang, LQ Li, F Hua, HD Lu… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Acute lung injury (ALI) and its final severe stage, acute respiratory distress
syndrome, are associated with high morbidity and mortality rates in patients due to the lack …

Pathogenic mechanisms and latest therapeutic approaches for radiation-induced lung injury: a narrative review

S Chang, J Lv, X Wang, J Su, C Bian, Z Zheng… - Critical Reviews in …, 2024 - Elsevier
The treatment of thoracic tumors with ionizing radiation can cause radiation-induced lung
injury (RILI), which includes radiation pneumonitis and radiation-induced pulmonary fibrosis …