Biothermodynamics of viruses from absolute zero (1950) to virothermodynamics (2022)

M Popovic - Vaccines, 2022 - mdpi.com
Biothermodynamics of viruses is among the youngest but most rapidly developing scientific
disciplines. During the COVID-19 pandemic, it closely followed the results published by …

[HTML][HTML] XBB. 1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB. 1.5 variant of SARS-CoV-2

ME Popovic - Microbiological research, 2023 - Elsevier
Abstract The SARS-CoV-2 Hydra with many heads (variants) has been causing the COVID-
19 pandemic for 3 years. The appearance of every new head (SARS-CoV-2 variant) causes …

Omicron BA. 2.75 subvariant of SARS-CoV-2 is expected to have the greatest infectivity compared with the competing BA. 2 and BA. 5, due to most negative Gibbs …

M Popovic - BioTech, 2022 - mdpi.com
Omicron BA. 2.75 may become the next globally dominant strain of COVID-19 in 2022. The
BA. 2.75 sub-variant has acquired more mutations (9) in spike protein and other genes of …

Omicron BA. 2.75 sublineage (centaurus) follows the expectations of the evolution theory: less negative gibbs energy of biosynthesis indicates decreased …

M Popovic - Microbiology Research, 2022 - mdpi.com
SARS-CoV-2 belongs to the group of RNA viruses with a pronounced tendency to mutate.
Omicron BA. 2.75 is a subvariant believed to be able to suppress the currently dominant BA …

Why doesn't Ebola virus cause pandemics like SARS-CoV-2?

M Popovic - Microbial risk analysis, 2022 - Elsevier
Ebola virus is among the most dangerous, contagious and deadly etiological causes of viral
diseases. However, Ebola virus has never extensively spread in human population and …

SARS-CoV-2 strain wars continues: Chemical and thermodynamic characterization of live matter and biosynthesis of Omicron BN. 1, CH. 1.1 and XBC variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 has during the last 3 years mutated several dozen times. Most mutations in the
newly formed variants have been chemically and thermodynamically characterized. New …

Never ending story? Evolution of SARS-CoV-2 monitored through Gibbs energies of biosynthesis and antigen-receptor binding of Omicron BQ. 1, BQ. 1.1, XBB and …

M Popovic - Microbial risk analysis, 2023 - Elsevier
RNA viruses exhibit a great tendency to mutate. Mutations occur in the parts of the genome
that encode the spike glycoprotein and less often in the rest of the genome. This is why …

The SARS-CoV-2 Hydra, a tiny monster from the 21st century: Thermodynamics of the BA. 5.2 and BF. 7 variants

M Popovic - Microbial Risk Analysis, 2023 - Elsevier
SARS-CoV-2 resembles the ancient mythical creature Hydra. Just like with the Hydra, when
one head is cut, it is followed by appearance of two more heads, suppression of one SARS …

Ghosts of the past: Elemental composition, biosynthesis reactions and thermodynamic properties of Zeta P. 2, Eta B. 1.525, Theta P. 3, Kappa B. 1.617. 1, Iota B. 1.526 …

M Popovic, MP Pavlović, M Pavlović - Microbial risk analysis, 2023 - Elsevier
From the perspectives of molecular biology, genetics and biothermodynamics, SARS-CoV-2
is the among the best characterized viruses. Research on SARS-CoV-2 has shed a new …

[PDF][PDF] COVID infection in 4 steps: Thermodynamic considerations reveal how viral mucosal diffusion, target receptor affinity and furin cleavage act in concert to drive …

M Popovic, JH Martin, RJ Head - Heliyon, 2023 - cell.com
We have developed a mechanistic model of SARS-CoV-2 and SARS-CoV infection,
exploring the relationship between the viral diffusion in the mucosa and viral affinity for the …