Targetable elements in SARS-CoV-2 S2 subunit for the design of pan-coronavirus fusion inhibitors and vaccines
L Guo, S Lin, Z Chen, Y Cao, B He, G Lu - Signal Transduction and …, 2023 - nature.com
The ongoing global pandemic of coronavirus disease 2019 (COVID-19), caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused devastating impacts …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused devastating impacts …
Therapeutic prospects of naturally occurring p38 MAPK inhibitors tanshinone IIA and pinocembrin for the treatment of SARS‐CoV‐2‐induced CNS complications
M Valipour - Phytotherapy Research, 2023 - Wiley Online Library
P38 mitogen‐activated protein kinase (p38 MAPK) signaling pathway is closely related to
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) replication and …
Gold nanoparticles combat enveloped RNA virus by affecting organelle dynamics
F Li, Q Huang, Z Zhou, Q Guan, F Ye… - … and Targeted Therapy, 2023 - nature.com
Enveloped RNA viruses are a group of viruses with an outer membrane derived from a host
cell and a genome consisting of ribonucleic acid (RNA). These viruses rely on host cell …
cell and a genome consisting of ribonucleic acid (RNA). These viruses rely on host cell …
The envelope (E) protein of SARS-coV-2 as a pharmacological target
T Santos-Mendoza - Viruses, 2023 - mdpi.com
The COVID-19 pandemic caused by the SARS-CoV-2 virus is still a global health concern.
Several spike (S) protein-based vaccines have been developed that efficiently protect the …
Several spike (S) protein-based vaccines have been developed that efficiently protect the …
Innate and adaptive immunity to SARS-CoV-2 and predisposing factors
J Shen, J Fan, Y Zhao, D Jiang, Z Niu, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus (SARS-CoV-2), has affected all countries worldwide. Although some …
syndrome coronavirus (SARS-CoV-2), has affected all countries worldwide. Although some …
An Overview on Anti-COVID-19 Drug Achievements and Challenges Ahead
M Valipour, H Irannejad, H Keyvani - ACS Pharmacology & …, 2023 - ACS Publications
The appearance of several coronavirus pandemics/epidemics during the last two decades
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …
(SARS-CoV-1 in 2002, MERS-CoV in 2012, and SARS-CoV-2 in 2019) indicates that …
Potential anti-SARS-CoV-2 prodrugs activated by phosphorylation and their role in the aged population
The COVID-19 pandemic has flared across every part of the globe and affected populations
from different age groups differently. People aged from 40 to 80 years or older are at an …
from different age groups differently. People aged from 40 to 80 years or older are at an …
In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases
AHE Hassan, SM El-Sayed, M Yamamoto, J Gohda… - Viruses, 2023 - mdpi.com
Coronaviruses, including SARS-CoV-2, SARS-CoV, MERS-CoV and influenza A virus,
require the host proteases to mediate viral entry into cells. Rather than targeting the …
require the host proteases to mediate viral entry into cells. Rather than targeting the …
Identification of potential TMPRSS2 inhibitors for COVID-19 treatment in Chinese medicine by computational approaches and surface plasmon resonance technology
R Yang, L Liu, D Jiang, L Liu, H Yang… - Journal of Chemical …, 2023 - ACS Publications
Background: Coronavirus disease-19 (COVID-19) pneumonia continues to spread in the
entire globe with limited medication available. In this study, the active compounds in …
entire globe with limited medication available. In this study, the active compounds in …
Fourteen immunomodulatory alkaloids and two prenylated phenylpropanoids with dual therapeutic approach for COVID-19: molecular docking and dynamics studies
The pandemic outbreak of COVID-19 caused by the new severe acute respiratory syndrome
coronavirus (SARS-CoV-2) is a global health burden. To date, there is no highly effective …
coronavirus (SARS-CoV-2) is a global health burden. To date, there is no highly effective …