Chronic kidney disease (CKD) is generally regarded as a final common pathway of several
renal diseases, often leading to end-stage kidney disease (ESKD) and a need for renal …

Absorbed dose heterogeneity in kidney tissues is an important issue in radiopharmaceutical
therapy. The effect of absorbed dose heterogeneity in nephrotoxicity is, however, not fully …

Acute and chronic kidney disease continues to confer significant morbidity and mortality in
the clinical setting. Despite high prevalence of these conditions, few validated biomarkers …

Background The diversity between the muscle cellular interactome of dependent and
independent elderly people is based on the interrelationships established between different …

Background and objectives: Oleanolic acid (OA) is a penta-cyclic triterpene with diverse
bioactivities such as anticarcinogenic, antiviral, antimicrobial, hepatoprotective, anti …

Background Chronic kidney disease (CKD) is a global public health concern. Therefore, to
provide timely intervention for non-hospitalized high-risk patients and rationally allocate …

Contrast-induced acute kidney injury (CI-AKI), which occurs after the use of iodinated
contrast media, has become the third leading cause of hospital-acquired acute kidney injury …

The kidneys are responsible for maintaining physiologic homeostasis. The kidneys clear a
variety of drugs and other substances through passive (filtration) and active processes that …

In order to transition a new chemical entity (NCE) from the discovery arena into nonclinical
development and potentially the clinic, a comprehensive nonclinical safety profile must be …

Acute kidney injury and impaired kidney function is associated with reduced survival and
increased morbidity. Porophyllum ruderale is an edible plant endemic to Mexico used in …