The gut microbiome in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation

R Masetti, D Zama, D Leardini… - Pediatric Blood & …, 2020 - Wiley Online Library
The gut microbiome (GM) has been associated with different clinical outcomes in the context
of allogeneic hematopoietic stem cell transplantation (HSCT). Large multicenter cohort …

Diagnosis, grading and management of toxicities from immunotherapies in children, adolescents and young adults with cancer

D Ragoonanan, SJ Khazal, H Abdel-Azim… - Nature Reviews …, 2021 - nature.com
Cancer immunotherapies are associated with remarkable therapeutic response rates but
also with unique and severe toxicities, which potentially result in rapid deterioration in …

[HTML][HTML] Antibiotic-induced depletion of anti-inflammatory clostridia is associated with the development of graft-versus-host disease in pediatric stem cell …

TR Simms-Waldrip, G Sunkersett, LA Coughlin… - Biology of Blood and …, 2017 - Elsevier
Adult stem cell transplantation (SCT) patients with graft-versus-host-disease (GVHD) exhibit
significant disruptions in gut microbial communities. These changes are associated with …

Early and late complications following hematopoietic stem cell transplantation in pediatric patients–A retrospective analysis over 11 years

S Hierlmeier, M Eyrich, M Wölfl, PG Schlegel… - PloS one, 2018 - journals.plos.org
Hematopoietic stem cell transplantation (HSCT) has been an effective method for treating a
wide range of malignant or non-malignant disorders. In case of an autologous HSCT …

The safety and feasibility of probiotics in children and adolescents undergoing hematopoietic cell transplantation

EJ Ladas, M Bhatia, L Chen, E Sandler… - Bone marrow …, 2016 - nature.com
Hematopoietic cell transplantation (HCT) has become a standard treatment for many adult
and pediatric conditions. Emerging evidence suggests that perturbations in the microbiota …

Viral reactivations following hematopoietic stem cell transplantation in pediatric patients–A single center 11-year analysis

F Düver, B Weißbrich, M Eyrich, M Wölfl, PG Schlegel… - PLoS …, 2020 - journals.plos.org
Viral reactivation occurs frequently in the context of immunodeficiency and
immunosuppression after allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

Gut microbiota diversity before allogeneic hematopoietic stem cell transplantation as a predictor of mortality in children

R Masetti, D Leardini, E Muratore, M Fabbrini… - Blood, 2023 - ashpublications.org
The correlation existing between gut microbiota diversity and survival after allogeneic
hematopoietic stem cell transplantation (allo-HSCT) has so far been studied in adults …

Mismatched related vs matched unrelated donors in TCRαβ/CD19-depleted HSCT for primary immunodeficiencies

A Laberko, E Sultanova, E Gutovskaya… - Blood, The Journal …, 2019 - ashpublications.org
Abstract TCRαβ+/CD19+ graft depletion effectively prevents graft-versus-host disease
(GVHD). In the current study, we compared the outcomes of hematopoietic stem cell …

Unrelated donor hematopoietic cell transplantation for hemophagocytic lymphohistiocytosis

KS Baker, AH Filipovich, TG Gross… - Bone marrow …, 2008 - nature.com
We report outcomes after unrelated donor hematopoietic cell transplantation (HCT) for 91
patients with hemophagocytic lymphohistiocytosis (HLH) transplanted in the US in 1989 …

[HTML][HTML] Impact of conditioning regimen on outcomes for children with acute myeloid leukemia undergoing transplantation in first complete remission. An analysis on …

G Lucchini, M Labopin, E Beohou, A Dalissier… - Biology of Blood and …, 2017 - Elsevier
Hematopoietic stem cell transplantation (HSCT) represents the cornerstone of treatment in
pediatric high-risk and relapsed acute myeloid leukemia (AML). The aim of the present study …