Impact of the mother's gut microbiota on infant microbiome and brain development

EA Mady, AS Doghish, WA El-Dakroury… - Neuroscience & …, 2023 - Elsevier
The link between the gut microbiome and health has recently garnered considerable interest
in its employment for medicinal purposes. Since the early microbiota exhibits more flexibility …

[HTML][HTML] The human microbiome and child growth–first 1000 days and beyond

RC Robertson, AR Manges, BB Finlay… - Trends in …, 2019 - cell.com
The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

[HTML][HTML] Microbial exposure during early human development primes fetal immune cells

A Mishra, GC Lai, LJ Yao, TT Aung, N Shental… - Cell, 2021 - cell.com
The human fetal immune system begins to develop early during gestation; however, factors
responsible for fetal immune-priming remain elusive. We explored potential exposure to …

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

C Milani, S Duranti, F Bottacini, E Casey… - Microbiology and …, 2017 - Am Soc Microbiol
The human gut microbiota is engaged in multiple interactions affecting host health during
the host's entire life span. Microbes colonize the neonatal gut immediately following birth …

[HTML][HTML] Aspects of gut microbiota and immune system interactions in infectious diseases, immunopathology, and cancer

V Lazar, LM Ditu, GG Pircalabioru, I Gheorghe… - Frontiers in …, 2018 - frontiersin.org
The microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, bringing to the host organism a dowry of cells and genes more numerous …

The gastrointestinal microbiome: a review

PC Barko, MA McMichael, KS Swanson… - Journal of veterinary …, 2018 - Wiley Online Library
The gastrointestinal microbiome is a diverse consortium of bacteria, archaea, fungi,
protozoa, and viruses that inhabit the gut of all mammals. Studies in humans and other …

Intestinal barrier and gut microbiota: Shaping our immune responses throughout life

T Takiishi, CIM Fenero, NOS Câmara - Tissue barriers, 2017 - Taylor & Francis
The gastrointestinal (GI) tract is considered the largest immunological organ in the body
having a central role in regulating immune homeostasis. Contrary to earlier belief, the …

[HTML][HTML] A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: implications for research on the pioneer infant microbiome

ME Perez-Muñoz, MC Arrieta, AE Ramer-Tait, J Walter - microbiome, 2017 - Springer
After more than a century of active research, the notion that the human fetal environment is
sterile and that the neonate's microbiome is acquired during and after birth was an accepted …

Maturation of the infant microbiome community structure and function across multiple body sites and in relation to mode of delivery

DM Chu, J Ma, AL Prince, KM Antony, MD Seferovic… - Nature medicine, 2017 - nature.com
Human microbial communities are characterized by their taxonomic, metagenomic and
metabolic diversity, which varies by distinct body sites and influences human physiology …

[HTML][HTML] The not-so-sterile womb: evidence that the human fetus is exposed to bacteria prior to birth

LF Stinson, MC Boyce, MS Payne… - Frontiers in microbiology, 2019 - frontiersin.org
The human microbiome includes trillions of bacteria, many of which play a vital role in host
physiology. Numerous studies have now detected bacterial DNA in first-pass meconium and …