Viral infections cause high morbidity and mortality, threaten public health, and impose a
socioeconomic burden. We have seen the recent emergence of SARS‐CoV‐2 (Severe …

Nucleosides and their derivatives are a well-known and well-described class of compounds
with antiviral activity. Currently, in the era of the COVID-19 pandemic, scientists are also …

Viral latency of human immunodeficiency virus type 1 (HIV-1) has become a major hurdle to
a cure in the highly effective antiretroviral therapy (ART) era. The clustered regularly …

Therapeutic nucleic acid drugs (antisense DNA, siRNA, DNAzyme, and others) have been
widely employed to regulate the expression of a disease‐causing gene. For the correction of …

The presence of latently infected cells and reservoirs in HIV-1 infected patients constitutes a
significant obstacle to achieve a definitive cure. Despite the efforts dedicated to solve these …

Abstract The CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)/Cas9
(CRISPR-associated protein 9) system enables scientists to edit diverse genome types with …

Almost 40 years ago, the world was noticing the emergence of one of the major public health
threats it has ever known: HIV. Facing the cost-effectiveness and the health-related issues …

The filamentous fungus Aspergillus niger is the foundation of modern biotechnology and is
still of great economic importance, especially with regards to the production of organic acids …

Chapter 3 through Chap. 11 introduces the current status of clinical applications of
polypharmacology to disease therapy. This chapter will describe the applications of …

Penyakit menular akibat virus merupakan salah satu masalah kesehatan global yang
mempengaruhi sistem kesehatan masyarakat dan ekonomi di seluruh dunia. Hal tersebut …