Metabolic regulation of type I interferon production

SM O'Carroll, FDR Henkel… - Immunological Reviews, 2024 - Wiley Online Library
Over the past decade, there has been a surge in discoveries of how metabolic pathways
regulate immune cell function in health and disease, establishing the field of …

[HTML][HTML] Metabolic regulation of tumor-associated macrophage heterogeneity: insights into the tumor microenvironment and immunotherapeutic opportunities

Y Qian, Y Yin, X Zheng, Z Liu, X Wang - Biomarker Research, 2024 - Springer
Tumor-associated macrophages (TAMs) are a heterogeneous population that play diverse
functions in tumors. Their identity is determined not only by intrinsic factors, such as origins …

[HTML][HTML] From periphery to center stage: 50 years of advancements in innate immunity

S Carpenter, LAJ O'Neill - Cell, 2024 - cell.com
Over the past 50 years in the field of immunology, something of a Copernican revolution has
happened. For a long time, immunologists were mainly concerned with what is termed …

[HTML][HTML] Songorine modulates macrophage polarization and metabolic reprogramming to alleviate inflammation in osteoarthritis

XX He, YJ Huang, CL Hu, QQ Xu, QJ Wei - Frontiers in Immunology, 2024 - frontiersin.org
Introduction Osteoarthritis (OA) is a prevalent joint disorder characterized by multifaceted
pathogenesis, with macrophage dysregulation playing a critical role in perpetuating …