Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

COVID-19 is a global pandemic impacting the daily living of millions. As variants of the virus
evolve, a complete comprehension of the disease and drug targets becomes a decisive …

SARS-CoV-2 RNA interacts with host factors to suppress interferon responses and
simultaneously induces cytokine release to drive the development of severe coronavirus …

Bioinformatics has played an important role in analyzing chemical information acquired
using mass spectrometry (MS) for large numbers of biological samples. Here we review the …

Multi-omic studies of the human gut microbiome are crucial for understanding its role in
disease across multiple functional layers. Nevertheless, integrating and analyzing such …

Background Immune dysregulation is a major factor in the development of severe
coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 …

A causal relationship between plasma ceramide concentration and respiratory distress
symptoms in COVID-19 patients is inferred. In this study, plasma samples of 52 individuals …

The clinical course of COVID-19 is variable and often unpredictable. To test the hypothesis
that disease progression and inflammatory responses associate with alterations in the …

The drug discovery and development (DDD) process in pursuit of novel drug candidates is a
challenging procedure requiring lots of time and resources. Therefore, computer-aided drug …

Cytosolic citrate is imported from the mitochondria by SLC25A1, and from the extracellular
milieu by SLC13A5. In the cytosol, citrate is used by ACLY to generate acetyl-CoA, which …