[HTML][HTML] Chemokines and chemokine receptors during COVID-19 infection

BA Khalil, NM Elemam, AA Maghazachi - Computational and structural …, 2021 - Elsevier
Chemokines are crucial inflammatory mediators needed during an immune response to
clear pathogens. However, their excessive release is the main cause of hyperinflammation …

JAK-STAT pathway inhibition and their implications in COVID-19 therapy

S Satarker, AA Tom, RA Shaji, A Alosious… - Postgraduate …, 2021 - Taylor & Francis
As the incidence of COVID-19 increases with time, more and more efforts are made to pave
a way out for the therapeutic strategies to deal with the disease progression. Inflammation …

[HTML][HTML] Oxidative stress status in COVID-19 patients hospitalized in intensive care unit for severe pneumonia. A pilot study

J Pincemail, E Cavalier, C Charlier, JP Cheramy–Bien… - Antioxidants, 2021 - mdpi.com
Background: A key role of oxidative stress has been highlighted in the pathogenesis of
COVID-19. However, little has been said about oxidative stress status (OSS) of COVID-19 …

SARS-CoV-2: Targeted managements and vaccine development

M Bakhiet, S Taurin - Cytokine & growth factor reviews, 2021 - Elsevier
Infection with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) results in
diverse outcomes. The symptoms appear to be more severe in males older than 65 and …

The impact of COVID-19 infection on the cytokine profile of pregnant women: A prospective case-control study

A Tanacan, N Yazihan, SA Erol, AT Anuk, FDY Yetiskin… - Cytokine, 2021 - Elsevier
Objective To compare the levels of various cytokines between pregnant women with
confirmed coronavirus disease (COVID-19) infection and pregnant women without any …

[HTML][HTML] Elucidating the neuropathologic mechanisms of SARS-CoV-2 infection

M Pacheco-Herrero, LO Soto-Rojas… - Frontiers in …, 2021 - frontiersin.org
The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus …

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease

B Canal, AW McClure, JF Curran, M Wu… - Biochemical …, 2021 - portlandpress.com
SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world
causing a deadly pandemic with tremendous social and economic costs. Healthcare …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

Galectin-9, a player in cytokine release syndrome and a surrogate diagnostic biomarker in SARS-CoV-2 infection

N Bozorgmehr, S Mashhouri, E Perez Rosero, L Xu… - MBio, 2021 - Am Soc Microbiol
The outbreak of SARS-CoV-2 infection has enormously impacted our lives. Clinical
evidence has implicated the emergence of cytokine release syndrome as the prominent …

[HTML][HTML] Glucocorticoids are double-edged sword in the treatment of COVID-19 and cancers

R Yang, Y Yu - International journal of biological sciences, 2021 - ncbi.nlm.nih.gov
Glucocorticoids are important steroid hormones. As an outstanding scientific discovery, the
scientist who discovered glucocorticoids was awarded the Nobel Prize in Physiology and …