[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Differential pathophysiological mechanisms in heart failure with a reduced or preserved ejection fraction in diabetes

M Packer - Heart Failure, 2021 - jacc.org
Diabetes promotes the development of both heart failure with a reduced ejection fraction
and heart failure with a preserved ejection fraction through diverse mechanisms, which are …

Epicardial adipose tissue and outcome in heart failure with mid-range and preserved ejection fraction

G van Woerden, DJ van Veldhuisen… - Circulation: Heart …, 2022 - Am Heart Assoc
Background: Epicardial adipose tissue (EAT) accumulation is thought to play a role in the
pathophysiology of heart failure (HF) with mid-range and preserved ejection fraction, but its …

Deep learning predicts cardiovascular disease risks from lung cancer screening low dose computed tomography

H Chao, H Shan, F Homayounieh, R Singh… - Nature …, 2021 - nature.com
Cancer patients have a higher risk of cardiovascular disease (CVD) mortality than the
general population. Low dose computed tomography (LDCT) for lung cancer screening …

Gender-based research underscores sex differences in biological processes, clinical disorders and pharmacological interventions

SR Bernstein, C Kelleher, RA Khalil - Biochemical Pharmacology, 2023 - Elsevier
Earlier research has presumed that the male and female biology is similar in most organs
except the reproductive system, leading to major misconceptions in research interpretations …

[PDF][PDF] SGLT2 抑制剂治疗心力衰竭潜在机制的新认识

廖梦阳, 廖玉华, 余淼, 陈霄, 袁璟, 程翔 - 临床心血管病杂志, 2022 - lcxxgen.whuhzzs.com
钠-葡萄糖协同转运蛋白2 (SGLT2) 抑制剂已成为治疗心力衰竭(心衰) 的新兴药物,
但其作用机制尚不清楚. 健康人心肌细胞仅表达SGLT1, SGLT2 定位在肾脏近曲小管和心外膜 …

Sex hormones, intestinal inflammation, and the gut microbiome: major influencers of the sexual dimorphisms in obesity

H Brettle, V Tran, GR Drummond, AE Franks… - Frontiers in …, 2022 - frontiersin.org
Obesity is defined as the excessive accumulation of body fat and is associated with an
increased risk of developing major health problems such as cardiovascular disease …

Targeting epicardial adipose tissue with exercise, diet, bariatric surgery or pharmaceutical interventions: a systematic review and meta‐analysis

N Launbo, EH Zobel, BJ von Scholten… - Obesity …, 2021 - Wiley Online Library
Epicardial adipose tissue (EAT) and pericardial adipose tissue (PAT) are metabolically
active fat depots implicated in cardiovascular disease, and EAT has potential as a novel …

The role of epicardial adipose tissue in the development of atrial fibrillation, coronary artery disease and chronic heart failure in the context of obesity and type 2 …

A Krishnan, H Sharma, D Yuan, AF Trollope… - Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are a significant burden globally and are especially
prevalent in obese and/or diabetic populations. Epicardial adipose tissue (EAT) surrounding …

Diagnosis of coronary artery disease in patients with type 2 diabetes mellitus based on computed tomography and pericoronary adipose tissue radiomics: a …

X Dong, N Li, C Zhu, Y Wang, K Shi, H Pan… - Cardiovascular …, 2023 - Springer
Background Patients with type 2 diabetes mellitus (T2DM) are highly susceptible to
cardiovascular disease, and coronary artery disease (CAD) is their leading cause of death …