[HTML][HTML] Research progress on Sirtuins (SIRTs) family modulators
M Chen, J Tan, Z Jin, T Jiang, J Wu, X Yu - Biomedicine & …, 2024 - Elsevier
Sirtuins (SIRTs) represent a class of nicotinamide adenine dinucleotide (NAD+)-dependent
protein deacetylases that exert a crucial role in cellular signal transduction and various …
protein deacetylases that exert a crucial role in cellular signal transduction and various …
The role of sirtuins in intervertebral disc degeneration: Mechanisms and therapeutic potential
H Tu, Q Gao, Y Zhou, L Peng, D Wu… - Journal of Cellular …, 2024 - Wiley Online Library
Intervertebral disc degeneration (IDD) is one of the main causes of low back pain, which
affects the patients' quality of life and health and imposes a significant socioeconomic …
affects the patients' quality of life and health and imposes a significant socioeconomic …
SIRT5‐Mediated Desuccinylation of RAB7A Protects Against Cadmium‐Induced Alzheimer's Disease‐Like Pathology by Restoring Autophagic Flux
P Deng, T Fan, P Gao, Y Peng, M Li, J Li… - Advanced …, 2024 - Wiley Online Library
Cadmium (Cd) is a neurotoxic contaminant that induces cognitive decline similar to that
observed in Alzheimer's disease (AD). Autophagic flux dysfunction is attributed to the …
observed in Alzheimer's disease (AD). Autophagic flux dysfunction is attributed to the …
Sirtuins Affect Cancer Stem Cells via Epigenetic Regulation of Autophagy
F Sipos, G Műzes - Biomedicines, 2024 - mdpi.com
Sirtuins (SIRTs) are stress-responsive proteins that regulate several post-translational
modifications, partly by acetylation, deacetylation, and affecting DNA methylation. As a …
modifications, partly by acetylation, deacetylation, and affecting DNA methylation. As a …
Knockdown of miR-135a-5p Promotes Mitophagy by Regulating FoxO1/PINK1/Parkin Signaling in Hepatoma Cells Exposed to Oxidative Stress
W Zhenchang, Z Wenfu, W Shanshan… - Current Proteomics, 2023 - ingentaconnect.com
Introduction: Excessive oxidative stress is always associated with hepatic disease, including
hepatitis, liver fibrosis, and hepatocellular carcinoma (HCC). Despite this, the intricate …
hepatitis, liver fibrosis, and hepatocellular carcinoma (HCC). Despite this, the intricate …
Hypoxia induces cardiomyocyte autophagy by regulating SIRT5 expression
W Yunle, H Wei, F Yuxuan - 2024 - researchsquare.com
Hypoxia induces cardiomyocyte autophagy by regulating SIRT5 expression Page 1 Page 1/17
Hypoxia induces cardiomyocyte autophagy by regulating SIRT5 expression Wang Yunle …
Hypoxia induces cardiomyocyte autophagy by regulating SIRT5 expression Wang Yunle …