HETE, the ω-hydroxylation product of arachidonic acid catalyzed by enzymes of the
cytochrome P450 (CYP) 4A and 4F gene families, is a bioactive lipid mediator with potent …

The mechanisms that control blood pressure are multifaceted including the sympathetic
nervous system and the renin-angiotensin system leading to vasoconstriction and sodium …

The incidence, severity and progression of autoimmune diseases (eg scleroderma, multiple
sclerosis, rheumatoid arthritis) and certain inflammatory diseases (eg asthma) are sex …

Hypertension is one of the leading risk factors for cardiovascular disease, myocardial
infarction, and stroke. There are gender differences in the prevalence of hypertension and in …

Diabetic cardiomyopathy (DCM) is a well-established complication of type 1 and type 2
diabetes associated with a high rate of morbidity and mortality. DCM is diagnosed at …

The growing number of people who identify themselves as transgender has gained
increased attention in recent years and will certainly impact personalized clinical practices …

Alterations of diurnal rhythms of blood pressure (BP) and reshaping of gut microbiota are
both independently associated with hypertension. However, the relationships between …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of
reproductive age, affecting approximately 10%. PCOS is diagnosed by the presence of at …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder that affects
reproductive-age women. Hyperandrogenemia is present in a significant fraction (~ 80%) of …

Abstract Background Urinary 20-hydroxyeicosatetraenoic acid (20-HETE) has been
associated with hypertension in women with elevated urinary cadmium (Cd) excretion rates …