Potential corporate uses of polygenic indexes: Starting a conversation about the associated ethics and policy issues

MN Meyer, NW Papageorge, E Parens… - The American Journal of …, 2024 - cell.com
Some commercial firms currently sell polygenic indexes (PGIs) to individual consumers,
despite their relatively low predictive power. It might be tempting to assume that because the …

Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects

KJ Karczewski, R Gupta, M Kanai, W Lu, K Tsuo… - medRxiv, 2024 - medrxiv.org
Large biobanks, such as the UK Biobank (UKB), enable massive phenome by genome-wide
association studies that elucidate genetic etiology of complex traits. However, individuals …

Do we really need a new definition of dyslexia? A commentary

M Snowling, C Hulme - Annals of dyslexia, 2024 - Springer
We provide a commentary on current debates about the definition of dyslexia. We agree with
others that dyslexia is best thought of as a dimensional disorder with the best established …

[HTML][HTML] Causal interpretations of family GWAS in the presence of heterogeneous effects

C Veller, M Przeworski, G Coop - bioRxiv, 2023 - ncbi.nlm.nih.gov
Family-based genome-wide association studies (GWAS) have emerged as a gold standard
for assessing causal effects of alleles and polygenic scores. Notably, family studies are often …

Social-Science Genomics: Progress, Challenges, and Future Directions

Rapid progress has been made in identifying links between human genetic variation and
social and behavioral phenotypes. Applications in mainstream economics are beginning to …

'Dysgenic fertility'is an ideological, not a scientific, concept. A Comment on:'Stability and change in male fertility patterns by cognitive ability across 32 birth cohorts' …

R Sear, C Townsend - Biology letters, 2023 - royalsocietypublishing.org
Recently Bratsberg & Rogeberg (2023) presented an analysis in Biology Letters of how
cognitive ability is associated with fertility in Norwegian men. Our concern relates to the …

Polygenic predictions of occupational status GWAS elucidate genetic and environmental interplay for intergenerational status transmission, careers, and health

ET Akimova, T Wolfram, X Ding, FC Tropf, MC Mills - bioRxiv, 2023 - biorxiv.org
Socioeconomic status (SES) stratifies society and impacts our health and life course. We
conducted the first sociologically informed GWAS on occupational status and prestige …

Population descriptors and behavioural genetic research

J Graves Jr - Nature Human Behaviour, 2024 - nature.com
The use of typological conceptions of race in science is not based in evidence. A recent
report from the National Academy of Sciences, Engineering, and Medicine, USA clarifies …

Beyond a Shared History: A Biosocial Perspective on Sociogenomics and Racism in Germany

MAN Aikins, YE Willems, D Fraemke… - KZfSS Kölner Zeitschrift …, 2024 - Springer
Recent advances in sociogenomics offer new opportunities to integrate genetic and
epigenetic measures into social science research on human lifespan development. Now …

Factors related to the severity of research misconduct administrative actions: An analysis of office of research integrity case summaries from 1993 to 2023

B Long, S Laux, B Lemon, A Guarente… - Accountability in …, 2023 - Taylor & Francis
We extracted, coded, and analyzed data from 343 Office of Research Integrity (ORI) case
summaries published in the Federal Register and other venues from May 1993 to July 2023 …