Treatment for COVID-19: An overview
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by
coronavirus-2 (SARS-CoV-2) that causes a severe acute respiratory syndrome, a …
coronavirus-2 (SARS-CoV-2) that causes a severe acute respiratory syndrome, a …
[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis
IM Tleyjeh, Z Kashour, M Damlaj, M Riaz… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study
JJ Manson, C Crooks, M Naja, A Ledlie… - The Lancet …, 2020 - thelancet.com
Background A subset of patients with severe COVID-19 develop a hyperinflammatory
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
syndrome, which might contribute to morbidity and mortality. This study explores a specific …
Coronaviruses: innate immunity, inflammasome activation, inflammatory cell death, and cytokines
The innate immune system acts as the first line of defense against pathogens, including
coronaviruses (CoVs). Severe acute respiratory syndrome (SARS)-CoV and Middle East …
coronaviruses (CoVs). Severe acute respiratory syndrome (SARS)-CoV and Middle East …
Different innate and adaptive immune responses to SARS-CoV-2 infection of asymptomatic, mild, and severe cases
R Carsetti, S Zaffina, E Piano Mortari, S Terreri… - Frontiers in …, 2020 - frontiersin.org
SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
[HTML][HTML] Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …
prevalence and easy transmission, which is expanding globally with no conventional …
Severe acute respiratory syndrome coronavirus 2–induced immune activation and death of monocyte-derived human macrophages and dendritic cells
Studies of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–infected
patients and experimentally infected animals indicate a critical role for augmented …
patients and experimentally infected animals indicate a critical role for augmented …
COVID-19 and the role of cytokines in this disease
A Hasanvand - Inflammopharmacology, 2022 - Springer
Studies have shown that SARS-CoV-2 has the ability to activate and mature proinflammatory
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
cytokines in the body. Cytokine markers are a group of polypeptide signalling molecules that …
Anakinra combined with methylprednisolone in patients with severe COVID-19 pneumonia and hyperinflammation: An observational cohort study
G Bozzi, D Mangioni, F Minoia, S Aliberti… - Journal of Allergy and …, 2021 - Elsevier
Background Immunomodulants have been proposed to mitigate severe acute respiratory
syndrome coronavirus 2–induced cytokine storm, which drives acute respiratory distress …
syndrome coronavirus 2–induced cytokine storm, which drives acute respiratory distress …