Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress

MJ Hossain, SMA Rahman - Expert Review of Anti-Infective …, 2021 - Taylor & Francis
Introduction The pathogenic and highly transmissible etiological agent, SARS-CoV-2, has
caused a serious threat COVID-19 pandemic. WHO has declared the epidemic a public …

Recent insights into emerging coronavirus: SARS-CoV-2

Z Shang, SY Chan, WJ Liu, P Li… - ACS infectious …, 2020 - ACS Publications
The SARS-CoV-2 outbreak that emerged at the end of 2019 has affected more than 58
million people with more than 1.38 million deaths and has had an incalculable impact on the …

Drug-based therapeutic strategies for COVID-19-infected patients and their challenges

K Zarkesh, E Entezar-Almahdi, P Ghasemiyeh… - Future …, 2021 - Future Medicine
Emerging epidemic-prone diseases have introduced numerous health and economic
challenges in recent years. Given current knowledge of COVID-19, herd immunity through …

Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trials

P Farhangnia, S Dehrouyeh, AR Safdarian… - International …, 2022 - Elsevier
In late 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged,
causing a global pandemic called COVID-19. Currently, there is no definitive treatment for …

[PDF][PDF] COVID-19: the new challenge for rheumatologists. One year later

I Puxeddu, F Ferro, E Bartoloni, E Elefante… - Clin Exp …, 2021 - clinexprheumatol.org
At the beginning of COVID-19, we underlined that this pandemic was a new challenge for
rheumatologists. On the one hand, it was necessary to clarify the impact of this new viral …

[HTML][HTML] Cytokine profiles associated with worse prognosis in a hospitalized Peruvian COVID-19 cohort

MJ Pons, B Ymaña, A Mayanga-Herrera… - Frontiers in …, 2021 - frontiersin.org
Cytokines, chemokines and growth factors present different expression profiles related to the
prognosis of COVID-19. We analyzed clinical parameters and assessed the expression of …

[HTML][HTML] Existing drugs considered as promising in COVID-19 therapy

E Janik, M Niemcewicz, M Podogrocki… - International Journal of …, 2021 - mdpi.com
COVID-19 is a respiratory disease caused by newly discovered severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The disease at first was identified in the city of …

[HTML][HTML] The safety and efficacy of anakinra, an interleukin-1 antagonist in severe cases of COVID-19: a systematic review and meta-analysis

MKR Somagutta, MKL Pormento, P Hamid… - Infection & …, 2021 - ncbi.nlm.nih.gov
This study aims to assess anakinra's safety and efficacy for treating severe coronavirus
disease 2019 (COVID-19). Numerous electronic databases were searched and finally 15 …

[HTML][HTML] Evolving Clinical Manifestations and Outcomes in COVID-19 Patients: A Comparative Analysis of SARS-CoV-2 Variant Waves in a Romanian Hospital Setting

V Briciu, DC Leucuta, M Muntean, A Radulescu… - Pathogens, 2023 - mdpi.com
The aim of this study was to evaluate differences in the clinical manifestations and outcomes
in hospitalized patients with COVID-19 in a single Romanian center during four pandemic …

[HTML][HTML] Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection

Z Bahari, Z Jangravi, H Ghoshooni, MR Afarinesh… - Inflammation …, 2021 - Springer
Abstract Objective Coronavirus disease 2019 (COVID-19) is a world-wide pandemic caused
by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). To date, treatment of …