In recent years, aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, has
been considered to be involved in aging phenotypes across several species. This receptor …

Acquired immune function shows recognizable changes over time with organismal aging.
These changes include T-cell dysfunction, which may underlie diminished resistance to …

While some individuals age without pathological memory impairments, others develop age‐
associated cognitive diseases. Since changes in cognitive function develop slowly over time …

Old age is associated with a greater burden of disease, including neurodegenerative
disorders such as Alzheimer's disease and Parkinson's disease, as well as other chronic …

Neurodegenerative diseases represent a formidable challenge to global health. As
advances in other areas of medicine grant healthy living into later decades of life, aging …

Idiopathic pulmonary fibrosis (IPF) is a fatal chronic lung disease characterized by
progressive scarring of the lung tissue, leading to respiratory failure. There is no cure for IPF …

Cell‐free DNA (cfDNA) is present in the circulating plasma and other body fluids and is
known to originate mainly from apoptotic cells. Here, we provide the first in vivo evidence of …

Centenarians are remarkable not only because of their prolonged life, but also because they
compress morbidity until the very last moments of their lives, thus being proposed as a …

Age‐related diseases such as cancer, cardiovascular disease, kidney failure, and
osteoarthritis have universal features: Their incidence rises exponentially with age with a …

The adult central nervous system (CNS) contains resident stem cells within specific niches
that maintain a self-renewal and proliferative capacity to generate new neurons, astrocytes …