National cancer institute collaborative workshop on shaping the landscape of brain metastases research: challenges and recommended priorities

MM Kim, MP Mehta, DDK Smart, PS Steeg… - The Lancet …, 2023 - thelancet.com
Brain metastases are an increasing global public health concern, even as survival rates
improve for patients with metastatic disease. Both metastases and the sequelae of their …

Epidemiology and management trends of neuro-oncology in Nigeria: A systematic review and pooled analysis

AEK Ukachukwu, A Seas, EC Oboh, E Paradie… - World Neurosurgery, 2024 - Elsevier
Objective Access to neuro-oncologic care in Nigeria has grown exponentially since the first
reported cases in the mid-1960s. In this systematic review and pooled analysis, we …

Preoperative frailty and 30-day mortality after resection of brain metastases: a multicenter surgical registry analysis of 11,038 patients

GP Skandalakis, K Medani, K Rumalla, JM Roy… - Neurosurgical …, 2023 - thejns.org
OBJECTIVE Surgery plays a key role in the management of brain metastases. Stratifying
surgical risk and individualizing treatment will help optimize outcomes because there is …

Advances in the molecular landscape of lung cancer brain metastasis

VGP Souza, RP de Araújo, MR Santesso, AL Seneda… - Cancers, 2023 - mdpi.com
Simple Summary Patients with lung cancer have high rates of brain metastasis (BM).
Despite available therapies, patient prognosis is poor. Studies have shown genetic …

Harnessing immunotherapy for brain metastases: insights into tumor–brain microenvironment interactions and emerging treatment modalities

D Zhou, Z Gong, D Wu, C Ma, L Hou, X Niu… - Journal of Hematology & …, 2023 - Springer
Brain metastases signify a deleterious milestone in the progression of several advanced
cancers, predominantly originating from lung, breast and melanoma malignancies, with a …

Neurotoxicity from old and new radiation treatments for brain tumors

R Soffietti, A Pellerino, F Bruno, A Mauro… - International Journal of …, 2023 - mdpi.com
Research regarding the mechanisms of brain damage following radiation treatments for
brain tumors has increased over the years, thus providing a deeper insight into the …

Laser interstitial thermal therapy for the treatment of primary and metastatic brain tumors: a systematic review and meta-analysis

M Alkazemi, YT Lo, H Hussein, M Mammi, S Saleh… - World Neurosurgery, 2023 - Elsevier
Background Laser interstitial thermal therapy (LITT) is a minimally invasive treatment option
for intracranial tumors that are challenging to treat via traditional methods; however, its …

[HTML][HTML] Mathematical modeling of brain metastases growth and response to therapies: A review

B Ocaña-Tienda, VM Pérez-García - Mathematical Biosciences, 2024 - Elsevier
Brain metastases (BMs) are the most common intracranial tumor type and a significant
health concern, affecting approximately 10% to 30% of all oncological patients. Although …

The origin of brain malignancies at the blood–brain barrier

B McDonald, K Barth, MHH Schmidt - Cellular and Molecular Life Sciences, 2023 - Springer
Despite improvements in extracranial therapy, survival rate for patients suffering from brain
metastases remains very poor. This is coupled with the incidence of brain metastases …

Theranostics in Neurooncology: Heading Toward New Horizons

N Tolboom, A Verger, NL Albert, F Fraioli… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Therapeutic approaches to brain tumors remain a challenge, with considerable limitations
regarding delivery of drugs. There has been renewed and increasing interest in translating …