In the 40 years since Aaron Beck first proposed his cognitive model of depression, the
elements of this model—biased attention, biased processing, biased thoughts and …

The beneficial clinical effects of mindfulness practices are receiving increasing support from
empirical studies. However, the functional neural mechanisms underlying these benefits …

Objective: The purpose of this article was to inform the first-line treatment choice between
cognitive-behavioral therapy (CBT) or an antidepressant medication for treatment-naive …

This review begins with a brief historical overview of attempts in the first half of the 20th
century to discern brain systems that underlie emotion and emotional behavior. These early …

The cerebellum has been considered for a long time to play a role solely in motor
coordination. However, studies over the past two decades have shown that the cerebellum …

There exists a divide between findings from integrative neuroscience and clinical research
focused on mechanisms of psychopathology. Specifically, a clear correspondence does not …

BACKGROUND: Positron emission tomography (PET) studies of major depression have
revealed resting-state abnormalities in the prefrontal and cingulate cortices. Recently, fMRI …

Depression has become the single most commonly treated mental disorder, amid claims that
one out of ten Americans suffer from this disorder every year and 25% succumb at some …

Recovery from emotional challenge and increased tolerance of negative affect are both
hallmarks of mental health. Mindfulness training (MT) has been shown to facilitate these …

The anterior cingulate cortex (ACC) ventral to the genu of the corpus callosum has been
implicated in the modulation of emotional behavior on the basis of neuroimaging studies in …