BACKGROUND Polycystic ovary syndrome (PCOS) is the most common cause of
anovulatory infertility. An endometrial component has been suggested to contribute to …

Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …

Women who have had repeated miscarriages often have uncertainties about the cause, the
likelihood of recurrence, the investigations they need, and the treatments that might help …

Recurrent pregnancy loss is an important reproductive health issue, affecting 2%–5% of
couples. Common established causes include uterine anomalies, antiphospholipid …

Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In
current reproductive medicine, progesterone and its analogues play crucial roles. While the …

The majority of miscarriages are sporadic and most result from genetic causes that are
greatly influenced by maternal age. Recurrent pregnancy loss (RPL) is defined by two or …

Progesterone is essential for the maintenance of pregnancy. Several small trials have
suggested that progesterone supplementation may reduce the risk of miscarriage in women …

Background Progesterone is essential for the maintenance of pregnancy. However, whether
progesterone supplementation in the first trimester of pregnancy would increase the rate of …

BACKGROUND Progesterone is a key hormonal regulator of the female reproductive
system. It plays a major role to prepare the uterus for implantation and in the establishment …