Angiotensin receptor blockade with candesartan attenuates atherosclerosis, plaque disruption, and macrophage accumulation within the plaque in a rabbit model
MT Johnstone, AS Perez, I Nasser, R Stewart… - Circulation, 2004 - Am Heart Assoc
Background—Little is known about whether direct angiotensin receptor blockade can
reduce atherosclerosis and plaque disruption. This study evaluated the effect of angiotensin …
reduce atherosclerosis and plaque disruption. This study evaluated the effect of angiotensin …
Angiotensin II Type-2 receptors modulate inflammation through signal transducer and activator of transcription proteins 3 phosphorylation and TNFα production
Angiotensin subtype-1 receptor (AT1R) influences inflammatory processes through
enhancing signal transducer and activator of transcription proteins 3 (STAT3) signal …
enhancing signal transducer and activator of transcription proteins 3 (STAT3) signal …
Review of the molecular pharmacology of Losartan and its possible relevance to stroke prevention in patients with hypertension
J Díez - Clinical therapeutics, 2006 - Elsevier
BACKGROUND:: The Losartan Intervention For End-point reduction in hypertension (LIFE)
study found that a losartan-based regimen, compared with an atenolol-based regimen …
study found that a losartan-based regimen, compared with an atenolol-based regimen …
[PDF][PDF] Angiotensin-II behaves as an endogenous pro-inflammatory molecule
UN Das - JAPI, 2005 - researchgate.net
Angiotensin-II regulates vascular tone, stimulates the release of pro-inflammatory cytokines,
activates NF-κB, increases oxidant stress, and suppresses nitric oxide synthesis, and thus, it …
activates NF-κB, increases oxidant stress, and suppresses nitric oxide synthesis, and thus, it …
Interaction between angiotensin II, osteoprotegerin, and peroxisome proliferator-activated receptor-γ in abdominal aortic aneurysm
CS Moran, B Cullen, JH Campbell… - Journal of vascular …, 2009 - karger.com
Abstract Background and Aims: Osteoprotegerin (OPG) has been associated with abdominal
aortic aneurysm (AAA) expansion. Angiotensin II (AngII) receptor blockade has been shown …
aortic aneurysm (AAA) expansion. Angiotensin II (AngII) receptor blockade has been shown …
[HTML][HTML] The augmenting effects of desolvation and conformational energy terms on the predictions of docking programs against mPGES-1
In this study we introduce a rescoring method to improve the accuracy of docking programs
against mPGES-1. The rescoring method developed is a result of extensive computational …
against mPGES-1. The rescoring method developed is a result of extensive computational …
Cyclooxygenase and prostaglandin synthases: roles in plaque stability and instability in humans
D Santovito, A Mezzetti, F Cipollone - Current opinion in lipidology, 2009 - journals.lww.com
Cyclooxygenase and prostaglandin synthases: roles in plaque... : Current Opinion in Lipidology
Cyclooxygenase and prostaglandin synthases: roles in plaque stability and instability in …
Cyclooxygenase and prostaglandin synthases: roles in plaque stability and instability in …
Endogenous activated angiotensin-(1-7) plays a protective effect against atherosclerotic plaques unstability in high fat diet fed ApoE knockout mice
J Yang, X Yang, X Meng, M Dong, T Guo, J Kong… - International journal of …, 2015 - Elsevier
Background and objective We recently found that exogenous angiotensin-(1-7)[Ang-(1-7)]
inhibits Angiotensin II (Ang-II)-induced atherosclerotic lesion formation and enhances …
inhibits Angiotensin II (Ang-II)-induced atherosclerotic lesion formation and enhances …
Coxibs, non‐steroidal anti‐inflammatory drugs and cardiovascular risk
M Hermann, F Ruschitzka - Internal medicine journal, 2006 - Wiley Online Library
The introduction of selective cyclooxygenase‐2 inhibitors offered the promise of similar
efficacy in pain control without the gastrointestinal effects associated with non‐selective non …
efficacy in pain control without the gastrointestinal effects associated with non‐selective non …
Effects of telmisartan on inflammatory cytokines and coronary plaque component as assessed on integrated backscatter intravascular ultrasound in hypertensive …
K Yamaguchi, T Wakatsuki, T Soeki, T Niki… - Circulation …, 2014 - jstage.jst.go.jp
Background: Telmisartan has unique pleiotropic effects in addition to renin-angiotensin
system (RAS)-inhibition effects. The aim of this study was to evaluate the effects of …
system (RAS)-inhibition effects. The aim of this study was to evaluate the effects of …