Marolo (Annona crassiflora) is an underutilized Brazilian Cerrado fruit with few reports in the
literature about its bioactive compounds and functional properties. In this context, the …

Cancer remains one of the most challenging diseases despite significant advances of early
diagnosis and therapeutic treatments. Cancerous tumors are composed of various cell types …

S-adenosylmethionine synthases (MATs) are responsible for production of S-
adenosylmethionine, the cofactor essential for various methylation reactions, production of …

Migraines are a common disease with limited treatment options and some dietary factors are
recognized to trigger headaches. Although migraine pathogenesis is not completely known …

Glycine is an essential one-carbon (C1) metabolite nested in a complex network of cellular
metabolism. Glycine and its related metabolic pathways have important biochemical and …

Purpose The combination of cisplatin and gemcitabine-based chemotherapy has been
recommended as a preferred regimen for pancreatic ductal adenocarcinoma (PDAC) …

在真核生物中, 作为表观遗传调控的常见机制, DNA 甲基化和组蛋白甲基化主要影响染色质结构
和基因的转录表达, 特别是在哺乳动物细胞基因表达调控, 维持基因组稳定性等方面起着重要的 …

Endogenous polyamines such as putrescine (Put), spermidine (Spd), and spermine (Spm)
affect adipocyte differentiation. In this study, we investigated the effect of exogenously …

Enteric infections such as coccidiosis and necrotic enteritis in broilers may have a large
influence on the endogenous amino acids (eAA) losses within the gastrointestinal tract (GIT) …

Tumor endothelial cells (TECs) reside in the inner lining of blood vessels and represent a
promising target for targeted cancer therapy. DNA methylation is a chemical process that …