The hippocampus is a multi-stage neural circuit that is critical for memory formation. Its
distinct anatomy has long inspired theories that rely on local interactions between neurons …

Calcium influx can be stimulated by various intra-and extracellular signals to set coordinated
gene expression programs into motion. As such, the precise regulation of intracellular …

Sensory processing in the neocortex requires both feedforward and feedback information
flow between cortical areas. In feedback processing, higher-level representations provide …

Behavioral timescale synaptic plasticity (BTSP) is a type of non-Hebbian synaptic plasticity
reported to underlie place field formation. Despite this important function, the molecular …

Neuronal mitochondria play important roles beyond ATP generation, including Ca2+ uptake,
and therefore have instructive roles in synaptic function and neuronal response properties …

Mitochondria-ER contact sites (MERCs) orchestrate many important cellular functions
including regulating mitochondrial quality control through mitophagy and mediating …

Neuronal plasticity has been shown to be causally linked to coincidence detection through
dendritic spikes (dSpikes). We demonstrate the existence of SPW-R-associated, branch …

Accumulating evidence from a wide range of studies, including behavioral, cellular,
molecular and computational findings, support a key role of dendrites in the encoding and …

Abstract Calcium (Ca 2+) overload therapy is an efficient cancer treatment modality that
increases aberrant cytoplasmic Ca 2+ accumulation and activates mitochondrial apoptotic …

Calcium directly controls or indirectly regulates numerous functions that are critical for
neuronal network activity. Intracellular calcium concentration is tightly regulated by …