The immunology of long COVID

DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

[HTML][HTML] The neurobiology of long COVID

M Monje, A Iwasaki - Neuron, 2022 - cell.com
Persistent neurological and neuropsychiatric symptoms affect a substantial fraction of
people after COVID-19 and represent a major component of the post-acute COVID-19 …

Long-term neurologic outcomes of COVID-19

E Xu, Y Xie, Z Al-Aly - Nature medicine, 2022 - nature.com
The neurologic manifestations of acute COVID-19 are well characterized, but a
comprehensive evaluation of postacute neurologic sequelae at 1 year has not been …

Distinguishing features of Long COVID identified through immune profiling

J Klein, J Wood, JR Jaycox, RM Dhodapkar, P Lu… - Nature, 2023 - nature.com
Post-acute infection syndromes may develop after acute viral disease. Infection with SARS-
CoV-2 can result in the development of a post-acute infection syndrome known as long …

[HTML][HTML] Serotonin reduction in post-acute sequelae of viral infection

AC Wong, AS Devason, IC Umana, TO Cox… - Cell, 2023 - cell.com
Post-acute sequelae of COVID-19 (PASC," Long COVID") pose a significant global health
challenge. The pathophysiology is unknown, and no effective treatments have been found to …

Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …

[HTML][HTML] Molecular and spatial signatures of mouse brain aging at single-cell resolution

WE Allen, TR Blosser, ZA Sullivan, C Dulac, X Zhuang - Cell, 2023 - cell.com
The diversity and complex organization of cells in the brain have hindered systematic
characterization of age-related changes in its cellular and molecular architecture, limiting …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

[HTML][HTML] ME/CFS and Long COVID share similar symptoms and biological abnormalities: road map to the literature

AL Komaroff, WI Lipkin - Frontiers in Medicine, 2023 - frontiersin.org
Some patients remain unwell for months after “recovering” from the acute COVID-19. They
develop persistent fatigue, cognitive problems, headaches, disrupted sleep, myalgias and …