The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

MF Osuchowski, MS Winkler, T Skirecki… - The Lancet …, 2021 - thelancet.com
The zoonotic SARS-CoV-2 virus that causes COVID-19 continues to spread worldwide, with
devastating consequences. While the medical community has gained insight into the …

Monocytes and Macrophages in COVID-19

R Knoll, JL Schultze, J Schulte-Schrepping - Frontiers in immunology, 2021 - frontiersin.org
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …

T cell response to SARS-CoV-2 infection in humans: A systematic review

M Shrotri, MCI van Schalkwyk, N Post, D Eddy… - PloS one, 2021 - journals.plos.org
Background Understanding the T cell response to SARS-CoV-2 is critical to vaccine
development, epidemiological surveillance and disease control strategies. This systematic …

[HTML][HTML] Natural killer cells in SARS-CoV-2 infection: pathophysiology and therapeutic implications

C Di Vito, F Calcaterra, N Coianiz, S Terzoli… - Frontiers in …, 2022 - frontiersin.org
Natural Killer (NK) cells are lymphocytes of the innate immunity that play a crucial role in the
control of viral infections in the absence of a prior antigen sensitization. Indeed, they display …

Cellular immune response to COVID-19 and potential immune modulators

X Zhou, Q Ye - Frontiers in Immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …

Severe COVID-19 is characterized by the co-occurrence of moderate cytokine inflammation and severe monocyte dysregulation

B Bonnet, J Cosme, C Dupuis, E Coupez, M Adda… - …, 2021 - thelancet.com
Background SARS-CoV-2 has been responsible for considerable mortality worldwide, owing
in particular to pulmonary failures such as ARDS, but also to other visceral failures and …

Innate immune response to SARS-CoV-2 infection: From cells to soluble mediators

D Ricci, MP Etna, F Rizzo, S Sandini, M Severa… - International journal of …, 2021 - mdpi.com
The vulnerability of humankind to SARS-CoV-2 in the absence of a pre-existing immunity,
the unpredictability of the infection outcome, and the high transmissibility, broad tissue …

Monocyte HLA‐DR measurement by flow cytometry in COVID‐19 patients: an interim review

I Benlyamani, F Venet, R Coudereau… - Cytometry Part …, 2020 - Wiley Online Library
Several months after the sudden emergence of SARS‐CoV‐2 and COVID‐19, the
understanding of the appropriate host immune response to a virus totally unknown of human …

The complexity of SARS-CoV-2 infection and the COVID-19 pandemic

MK da Silva Torres, CDA Bichara… - Frontiers in …, 2022 - frontiersin.org
The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) led to the death of millions of people worldwide and thousands more infected individuals …

Natural killer cells in COVID-19: from infection, to vaccination and therapy

A Zafarani, MH Razizadeh, S Pashangzadeh… - Future …, 2023 - Taylor & Francis
Natural killer (NK) cells are among the most important innate immunity members, which are
the first cells that fight against infected cells. The function of these cells is impaired in …