Targeting mitochondrial metabolism for precision medicine in cancer

L Sainero-Alcolado, J Liaño-Pons… - Cell Death & …, 2022 - nature.com
During decades, the research field of cancer metabolism was based on the Warburg effect,
described almost one century ago. Lately, the key role of mitochondria in cancer …

Anti-cancer effects of green tea epigallocatchin-3-gallate and coffee chlorogenic acid

S Hayakawa, T Ohishi, N Miyoshi, Y Oishi, Y Nakamura… - Molecules, 2020 - mdpi.com
Tea and coffee are consumed worldwide and epidemiological and clinical studies have
shown their health beneficial effects, including anti-cancer effects. Epigallocatechin gallate …

Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis

Z Wu, S Huang, T Li, N Li, D Han, B Zhang, ZZ Xu… - Microbiome, 2021 - Springer
Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …

[HTML][HTML] Sulforaphane: A broccoli bioactive phytocompound with cancer preventive potential

AE Kaiser, M Baniasadi, D Giansiracusa… - Cancers, 2021 - mdpi.com
There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …

Innovative nanomaterials for cancer diagnosis, imaging, and therapy: Drug delivery applications

M Pourmadadi, MM Eshaghi, S Ostovar… - Journal of Drug Delivery …, 2023 - Elsevier
The emergence of nanomedicine drugs as a result of the fast advancement of
nanotechnology offers enormous potential for improving cancer treatment strategies. The …

Epigallocatechin gallate: Phytochemistry, bioavailability, utilization challenges, and strategies

S Mehmood, M Maqsood, N Mahtab… - Journal of Food …, 2022 - Wiley Online Library
Epigallocatechin gallate (EGCG), a green tea catechin, has gained the attention of current
study due to its excellent health‐promoting effects. It possesses anti‐obesity, antimicrobial …

[HTML][HTML] EGCG adjuvant chemotherapy: Current status and future perspectives

L Wang, P Li, K Feng - European journal of medicinal chemistry, 2023 - Elsevier
The resistance of cancer cells to chemotherapeutic drugs greatly reduces the therapeutic
effect in cancer patients, and the toxic side effects caused by chemotherapy also seriously …

Advanced phytochemical-based nanocarrier systems for the treatment of breast cancer

VP Chavda, LV Nalla, P Balar, R Bezbaruah… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a concern for the healthcare system. Even with the
advancement of science and technology, the current system for therapeutics and diagnostics …

Encapsulation of polyphenolic compounds for health promotion and disease prevention: Challenges and opportunities

SA Adefegha, A Salawi, A Bumrungpert… - Nano Micro …, 2022 - nmb-journal.com
Polyphenolic compounds are present in different parts of plants, including the root, stem,
bark, leaves, seeds and fruits. They have been reported for their various biological functions …

Chemico-biological aspects of (−)-epigallocatechin-3-gallate (EGCG) to improve its stability, bioavailability and membrane permeability: Current status and future …

R Sahadevan, S Singh, A Binoy… - Critical Reviews in Food …, 2023 - Taylor & Francis
Natural products have been a bedrock for drug discovery for decades.(−)-Epigallocatechin-3-
gallate (EGCG) is one of the widely studied natural polyphenolic compounds derived from …