Testosterone is the most important hormone in male health. Aging is characterized by
testosterone deficiency due to decreasing testosterone levels associated with low testicular …

Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

Male hypogonadism (MH) is a common endocrine disorder. However, uncertainties and
variations in its diagnosis and management exist. There are several current guidelines on …

Increased longevity and population aging will increase the number of men with late onset
hypogonadism. It is a common condition, but often underdiagnosed and undertreated. The …

Brain-derived neurotrophic factor (BDNF) is one of the key molecules modulating brain
plasticity. While low circulating levels of BDNF have been suggested to predispose to …

Background Mild cognitive impairment (MCI), a common condition among the elderly, is
defined as a deterioration of memory, attention, and cognitive function that exceeds what …

Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

Literature investigating whether an individuals' sex affects their executive control abilities
and performance on cognitive tasks in a normative population has been contradictory and …

Background Androgen deprivation therapy (ADT) is the backbone of systemic therapy for
men with prostate cancer (PC); almost one-half of patients receive treatment during their …

Alzheimer's disease (AD) is a neurodegenerative disease responsible for almost half of all
dementia cases in the world and progressively increasing. The etiopathology includes …