Background Exposure to maternal immune activation (MIA) in utero is a risk factor for
neurodevelopmental disorders later in life. The impact of the gestational timing of MIA …

Schizophrenia is regarded as a neurodevelopmental disorder with its course progressing
throughout life. However, the aetiology and development of schizophrenia are still under …

Prenatal infections have been linked to the development of schizophrenia (SCZ) and other
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …

It has been found that soluble epoxide hydrolase (sEH; encoded by the EPHX2 gene) in the
metabolism of polyunsaturated fatty acids (PUFAs) plays a key role in inflammation, which …

Schizophrenia is a major psychotic disorder with multifactorial etiology that includes
interactions between genetic vulnerability and environmental risk factors. In addition …

Inflammation during prenatal development can be detrimental to neurodevelopmental
processes, increasing the risk of neuropsychiatric disorders. Prenatal exposure to maternal …

Background Consistent with postmortem findings in patients, most animal models for
schizophrenia (SCZ) present abnormal levels of parvalbumin (PV), a marker of fast-spiking …

Objective: The goal of this article is to review the past decade's literature and provide a
critical commentary on the involvement of immunological mechanisms in normal brain …

Background Exposure to polyriboinosinic-polyribocytidylic acid (Poly I: C) in pregnant rats
has been reported to cause schizophrenia-like behaviors and abnormal neurotransmissions …

Despite decades of investigation into the genetics of autism spectrum disorder (ASD), a
current consensus in the field persists that ASD risk is too heterogeneous to be diagnosed …