Alteration of host cell splicing is a common feature of many viral infections which is underappreciated because of the complexity and technical difficulty of studying alternative …
Y Lv, T Zhang, J Cai, C Huang, S Zhan… - Frontiers in …, 2022 - frontiersin.org
Background The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global crisis. Although many people recover from COVID …
A Stéphanou, E Fanchon, PF Innominato, A Ballesta - Acta biotheoretica, 2018 - Springer
Abstract Systems biology is today such a widespread discipline that it becomes difficult to propose a clear definition of what it really is. For some, it remains restricted to the genomic …
Bioinformatics is inherently an innovative field that is situated at the limit of life and computer sciences that allowed new technological advances in genome sequencing, data processing …
S Schleidgen, S Fernau, H Fleischer… - BMC health services …, 2017 - Springer
Background Systems medicine has become a key word in biomedical research. Although it is often referred to as P4-(predictive, preventive, personalized and participatory)-medicine, it …
X Lu, X Wu, L Jing, L Tao, Y Zhang… - Evidence‐Based …, 2020 - Wiley Online Library
Objective. To analyze the active compounds, potential targets, and diseases of JianPi Fu Recipe (JPFR) based on network pharmacology and bioinformatics and verify the potential …
C Lemmen, C Woopen, S Stock - Health Policy, 2021 - Elsevier
Introduction Systems medicine is based on approaches taken from systems biology, omics research, bio-informatics and network theory. It promises to facilitate a better understanding …
B Fleisher, AN Brown, S Ait-Oudhia - Pharmacological Research, 2017 - Elsevier
Breast cancer (BC) is the most common cancer in women, and the second most frequent cause of cancer-related deaths in women worldwide. It is a heterogeneous disease …
Background High-throughput technologies are rapidly generating large amounts of diverse omics data. Although this offers a great opportunity, it also poses great challenges as data …