Childhood maltreatment and characteristics of adult depression: meta-analysis

J Nelson, A Klumparendt, P Doebler… - The British Journal of …, 2017 - cambridge.org
BackgroundChildhood maltreatment has been discussed as a risk factor for the
development and maintenance of depression. AimsTo examine the relationship between …

[HTML][HTML] Prevalence, course, and determinants of suicide ideation and attempts in patients with a depressive and/or anxiety disorder: A review of NESDA findings

JXM Wiebenga, J Dickhoff, SYM Mérelle… - Journal of affective …, 2021 - Elsevier
Background Depressive and anxiety disorders are often associated with suicide ideation (SI)
and attempt (SA). However, analyses of prevalence, course, and more specific risk …

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

R Karlsson Linnér, P Biroli, E Kong, SFW Meddens… - Nature …, 2019 - nature.com
Humans vary substantially in their willingness to take risks. In a combined sample of over 1
million individuals, we conducted genome-wide association studies (GWAS) of general risk …

Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

RC Culverhouse, NL Saccone, AC Horton, Y Ma… - Molecular …, 2018 - nature.com
The hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is
associated with increased risk of depression, but only in individuals exposed to stressful …

Effect of polygenic risk scores on depression in childhood trauma

WJ Peyrot, Y Milaneschi, A Abdellaoui… - The British Journal of …, 2014 - cambridge.org
BackgroundResearch on gene× environment interaction in major depressive disorder
(MDD) has thus far primarily focused on candidate genes, although genetic effects are …

Gene environment interaction studies in depression and suicidal behavior: an update

L Mandelli, A Serretti - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Increasing evidence supports the involvement of both heritable and environmental risk
factors in major depression (MD) and suicidal behavior (SB). Studies investigating gene …

Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors

D Suri, CM Teixeira, MKC Cagliostro… - …, 2015 - nature.com
Abstract Development passes through sensitive periods, during which plasticity allows for
genetic and environmental factors to exert indelible influence on the maturation of the …

Socioeconomic inequalities in psychological distress among urban adults: the moderating role of neighborhood social cohesion

Ö Erdem, FJ Van Lenthe, RG Prins, TAJJ Voorham… - PloS one, 2016 - journals.plos.org
Background Various studies have reported socioeconomic inequalities in mental health
among urban residents. This study aimed at investigating whether neighborhood social …

Gene–environment interactions in genome‐wide association studies: current approaches and new directions

SJ Winham, JM Biernacka - Journal of Child Psychology and …, 2013 - Wiley Online Library
Background Complex psychiatric traits have long been thought to be the result of a
combination of genetic and environmental factors, and gene–environment interactions are …

Suicidal behaviors and adverse childhood experiences: a cross-diagnostic study in persistent depressive disorder and borderline personality disorder

J Wolf, MA Reinhard, S Goerigk, BB Barton… - Psychiatry …, 2023 - Elsevier
Adverse childhood experiences (ACE) constitute a known risk factor for suicidality. There is
a research gap regarding differential patterns of associations between variants of suicidal …