Bordetella pertussis and Bordetella bronchiseptica are respiratory pathogens of humans
and animals respectively. Unlike many bacteria, they are able to efficiently colonise healthy …

During the course of a giardial infection, the host's immune system is presented with a
variety of Giardia antigens as trophozoites differentiate, through encysting cells, to form the …

The ability to express antigens from respiratory pathogens and induce immune responses
during oral colonization suggests that S. gordonii may be developed into a live vector for …

NadA and NhhA, two surface proteins of serogroup B Neisseria meningitidis identified as
candidate vaccine antigens, were expressed on the surface of the human oral commensal …

The antigen-specific primary activation of CD4+ T cells was studied in vivo by adoptive
transfer of ovalbumin-specific transgenic T cells (KJ1-26+ CD4+) following intranasal …

Urinary tract infections (UTIs) caused by Escherichia coli and Proteus mirabilis are an
important cause of morbidity and with the high rate of relapse and spread of multi-drug …

Streptococcus gordonii is a bacterial vaccine vector which has previously been shown to
activate dendritic cells in vitro and to induce local and systemic immune responses in vivo. In …

Bacterial cell division ends with the separation of the daughter cells, a process that requires
peptidoglycan hydrolases (PGHs). Bacteria lacking cell separating PGHs are impaired in …

Vaccinations against various antigens of the central nervous system (CNS) are gaining
increasing interest as a therapeutic approach in a variety of neurological diseases such as …

Novel surface proteins can be introduced onto bacterial cell surfaces by recombinant
means. Here, we describe various applications of two such display systems for the food …