Anaesthetics and cardiac preconditioning. Part II. Clinical implications

M Zaugg, E Lucchinetti, C Garcia… - British journal of …, 2003 - academic.oup.com
There is compelling evidence that preconditioning occurs in humans. Experimental studies
with potential clinical implications as well as clinical studies evaluating ischaemic …

Cardiac ECMO for biventricular hearts after paediatric open heart surgery

RR Chaturvedi, D Macrae, KL Brown, M Schindler… - Heart, 2004 - heart.bmj.com
Objective: To delineate predictors of hospital survival in a large series of children with
biventricular physiology supported with extracorporeal membrane oxygenation (ECMO) after …

Bradykinin-induced preconditioning in patients undergoing coronary angioplasty

MA Leesar, MF Stoddard, S Manchikalapudi… - Journal of the American …, 1999 - jacc.org
OBJECTIVES The purpose of this study was to determine whether administration of
bradykinin reproduces the cardioprotective effects of ischemic preconditioning (PC) in …

Adenosine receptors and reperfusion injury of the heart

JP Headrick, RD Lasley - Adenosine receptors in health and disease, 2009 - Springer
Adenosine, a catabolite of ATP, exerts numerous effects in the heart, including modulation of
the cardiac response to stress, such as that which occurs during myocardial ischemia and …

Ischemic preconditioning: protection against myocardial necrosis and apoptosis

EK Iliodromitis, A Lazou… - Vascular health and risk …, 2007 - Taylor & Francis
The phenomenon of ischemic preconditioning has been recognized as one of the most
potent mechanisms to protect against myocardial ischemic injury. In experimental animals …

Effects of naloxone on myocardial ischemic preconditioning in humans

F Tomai, F Crea, A Gaspardone, F Versaci… - Journal of the American …, 1999 - jacc.org
OBJECTIVES We attempted to establish whether naloxone, an opioid receptor antagonist,
abolishes the adaptation to ischemia observed in humans during coronary angioplasty after …

Ischaemic preconditioning: mechanisms and potential clinical applications

A Hawaleshka, E Jacobsohn - Canadian journal of anaesthesia, 1998 - Springer
Purpose Brief ischaemic episodes, followed by periods of reperfusion, increase the
resistance to further ischaemic damage. This response is called “ischaemic …

Evidence for a role for both the adenosine A1 and A3 receptors in protection of isolated human atrial muscle against simulated ischaemia

CS Carr, RJ Hill, H Masamune… - Cardiovascular …, 1997 - academic.oup.com
Objective: Adenosine receptor activation has been implicated in the mechanism of
ischaemic preconditioning protection. Evidence suggests adenosine A1 receptor …

Ticagrelor enhances the cardioprotective effects of ischemic preconditioning in stable patients undergoing percutaneous coronary intervention: the TAPER-S …

D D'Amario, M Galli, A Restivo… - European Heart …, 2024 - academic.oup.com
Background Ticagrelor improves clinical outcomes in patients with acute coronary
syndromes compared with clopidogrel. Ticagrelor also inhibits cell uptake of adenosine and …

Preconditioning− endogenous defence mechanisms of the heart

HT Sommerschild, KA Kirkebøen - Acta anaesthesiologica …, 2002 - Wiley Online Library
The term 'preconditioning'refers to the paradoxical phenomenon that pretreatment with a
potential noxious stress‐stimulus can increase cellular tolerance to subsequent noxious …