Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants
A broadly protective vaccine for COVID-19 is needed to end the pandemic and to prevent its
future recurrence. While the first-generation, spike-based vaccines are effective against …
future recurrence. While the first-generation, spike-based vaccines are effective against …
A Randomized, Double-Blind, Dose-Ascending, Placebo-Controlled Phase 1-2 Trial of Inhaled IBIO123: A Monoclonal Antibodies Cocktail Treatment for Mild-To …
B Maranda, SM Labbé, M Lurquin, P Brabant, A Fugère… - 2023 - papers.ssrn.com
Background: Coronavirus 2019 (COVID-19) disease severity is correlated to its respiratory
manifestations. Neutralizing antibodies against severe acute respiratory syndrome …
manifestations. Neutralizing antibodies against severe acute respiratory syndrome …
AAV-vector based vaccines for pandemic viruses: Evaluation of broadly reactive responses against influenza A viruses and SARS-CoV-2
S Stelzer - 2024 - refubium.fu-berlin.de
Influenza-A-Viren und SARS-CoV-2 stellen weiterhin eine ernsthafte Bedrohung für die
öffentliche Gesundheit dar. Beides sind zoonotische Erreger, die durch enge Kontakte …
öffentliche Gesundheit dar. Beides sind zoonotische Erreger, die durch enge Kontakte …
Immune Responses Following Administration of Whole Gamma Irradiated SARS-CoV-2 Vaccine Stabilized With Disaccharide Trehalose on Syrian Hamster Model
Background The SARS-CoV-2 virus is the causative agent of the emerging respiratory
zoonosis disease. One of the most important requirements for the control of emerging …
zoonosis disease. One of the most important requirements for the control of emerging …
Lasting first impression: Pre-existing immunity restricts mucosal antibody responses during Omicron breakthrough
Understanding mucosal antibody responses from SARS-CoV-2 infection and/or vaccination
is crucial to develop strategies for longer term immunity, especially against emerging viral …
is crucial to develop strategies for longer term immunity, especially against emerging viral …
Development of a novel SARS-CoV-2 Vaccination Strategy with a monomeric Spike Designer Antigen to prime efficient Antibody Responses in aged Mice
D Pflumm - 2024 - oparu.uni-ulm.de
The global COVID-19 pandemic has resulted in millions of deaths worldwide and the fastest
approval of newly developed SARS-CoV-2 vaccines ever. Based on the TM-anchored S …
approval of newly developed SARS-CoV-2 vaccines ever. Based on the TM-anchored S …
Pre-exposure prophylaxis for COVID-19 with Tix-agevimab/Cilgavimab in kidney transplant recipients in the Kraken variant (XBB. 1.5) era: A Single-center Experience
B Pinchera, R Carrano, F Salemi, A Piccione… - 2023 - preprints.org
Pre-exposure prophylaxis for COVID-19 with Tixagevimab/Cilgavimab in
immunocompromised patients has reduced the risk of breakthrough infection, disease …
immunocompromised patients has reduced the risk of breakthrough infection, disease …
[PDF][PDF] Monoclonal Antibodies in Hospitalised Patients with COVID-19: The Role of SARS-COV-2 Serostatus in an Evolving Pandemic
FRRL Gottlieb - 2023 - scienceopen.com
Appropriately selected neutralising monoclonal antibodies (nmAbs) are an effective
treatment for patients with mild or moderate coronavirus disease 2019 (COVID-19) who are …
treatment for patients with mild or moderate coronavirus disease 2019 (COVID-19) who are …
Antigen binding molecules targeting SARS-CoV-2
F Borriello, AH Ramos - US Patent 11,993,644, 2024 - Google Patents
BNMFQWUHWYJTRI-BQFCYCMXSA-N 7-chloro-N-[(2S)-1-[[(1S)-1-cyano-2-[(3S)-2-
oxopiperidin-3-yl] ethyl] amino]-3-cyclopropyl-1-oxopropan-2-yl]-1H-indole-2-carboxamide …
oxopiperidin-3-yl] ethyl] amino]-3-cyclopropyl-1-oxopropan-2-yl]-1H-indole-2-carboxamide …
Antigen binding molecules targeting SARS-CoV-2
G Grigoryan, J Ingraham - US Patent 11,987,616, 2024 - Google Patents
The invention provides, in various embodiments, polypeptides (eg, camelid antibodies and
antigen binding fragments thereof) that specifically bind to Spike glycoprotein of severe …
antigen binding fragments thereof) that specifically bind to Spike glycoprotein of severe …