Social epigenomics is a new field of research that studies how the social environment
shapes the epigenome and how in turn the epigenome modulates behavior. We focus on …

Expression quantitative trait loci (eQTLs) are used to inform the mechanisms of
transcriptional regulation in eukaryotic cells. However, the specificity of genome-wide eQTL …

Background Significant changes in CpG methylation have been identified in nasal polyps,
which are the main targets of nonsteroidal anti-inflammatory drug-exacerbated respiratory …

When differentially expressed genes are detected from samples containing different types of
cells, only a very coarse overview without any cell type-specific information is obtained …

Motivation Complex biological tissues are often a heterogeneous mixture of several
molecularly distinct cell subtypes. Both subtype compositions and subtype-specific (STS) …

Introduction Early life under-and overnutrition (jointly termed malnutrition) is increasingly
recognized as an important risk factor for adult obesity and metabolic syndrome, a diet …

Deconvolution is an efficient approach for detecting cell-type-specific (cs) transcriptomic
signals without cellular segmentation. However, this type of methods may require a …

Identification of cell-specific epigenetic patterns associated with chondroitin sulfate treatment
response in an endemic arthrit Page 1 Identification of cell-specific epigenetic patterns …

Understanding the intricate relationships between gene expression levels and epigenetic
modifications in a genome is crucial to comprehending the pathogenic mechanisms of many …

Motivation Complex tissues are dynamic ecosystems consisting of molecularly distinct yet
interacting cell types. Computational deconvolution aims to dissect bulk tissue data into cell …