Procyanidins, the oligomeric compounds formed from catechin and epicatechin molecules,
are potentially effective targets as nutraceuticals or pharmaceuticals in the prevention and …

Age-associated cognitive decline is an inevitable phenomenon that predisposes individuals
for neurological and psychiatric disorders eventually affecting the quality of life. Scientists …

Neuroinflammation is one of the important factors aggravating brain injury after ischemic
stroke. We aimed to investigate the effects of cerebrolysin (CBL) on neuroinflammation in …

Methamphetamine (METH) is abused by about 5% of the United States population with
approximately 10–15% of human immunodeficiency virus-1 (HIV-1) patients reporting its …

Chronic traumatic stress results in various psychiatric disorders, especially posttraumatic
stress disorder (PTSD). Previous study demonstrated that curculigoside (CUR) a component …

Introduction Alzheimer's disease (AD) is the most common progressive neurodegenerative
disease for which there is no cure. Recent studies have shown a close link between type 2 …

Background Alzheimer's disease (AD) causes progressive loss of memory and cognition,
exacerbated by APOE4, the greatest genetic risk factor for AD. One proposed mechanism for …

Normal aging is accompanied by hippocampus-dependent cognitive impairment, which is a
risk factor of Alzheimer's disease. This study aims to investigate the effect of high frequency …

Mitochondrial dysfunction has been linked to several neurodegenerative diseases such as
Parkinson's disease (PD). Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC …

In mammals during aging, reactive oxygen species (ROS), produced by the mitochondrial
respiratory chain, cause oxidative damage of macromolecules leading to respiratory chain …