An updated review on EPR-based solid tumor targeting nanocarriers for cancer treatment

M Sharifi, WC Cho, A Ansariesfahani, R Tarharoudi… - Cancers, 2022 - mdpi.com
Simple Summary One of the important efforts in the treatment of cancers is to achieve
targeted drug delivery by nanocarriers to be more effective and reduce adverse effects …

Rationally designed drug delivery systems for the local treatment of resected glioblastoma

C Bastiancich, A Malfanti, V Préat, R Rahman - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …

[HTML][HTML] The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy

Y Shi, R van der Meel, X Chen, T Lammers - Theranostics, 2020 - ncbi.nlm.nih.gov
Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …

Engineering oxygen-deficient ZrO2-x nanoplatform as therapy-activated “immunogenic cell death (ICD)” inducer to synergize photothermal-augmented sonodynamic …

X Jiao, L Sun, W Zhang, J Ren, L Zhang, Y Cao, Z Xu… - Biomaterials, 2021 - Elsevier
Nano-zirconia, as an amphoteric semiconductor, has been industrially exploited in
photocatalytic reactions and as piezoelectric sensors. However, its biomedical applications …

The Janus of Protein Corona on nanoparticles for tumor targeting, immunotherapy and diagnosis

X Wang, W Zhang - Journal of Controlled Release, 2022 - Elsevier
The therapeutics based on nanoparticles (NPs) are considered as the promising strategy for
tumor detection and treatment. However, one of the most challenges is the adsorption of …

Metal and metal oxides nanoparticles and nanosystems in anticancer and antiviral theragnostic agents

TI Shabatina, OI Vernaya, NL Shimanovskiy… - Pharmaceutics, 2023 - mdpi.com
The development of antiviral treatment and anticancer theragnostic agents in recent
decades has been associated with nanotechnologies, and primarily with inorganic …

Toward predicting nanoparticle distribution in heterogeneous tumor tissues

P MacMillan, AM Syed, BR Kingston, J Ngai… - Nano Letters, 2023 - ACS Publications
Nanobio interaction studies have generated a significant amount of data. An important next
step is to organize the data and design computational techniques to analyze the nanobio …

Targeting drug delivery in the vascular system: Focus on endothelium

PM Glassman, JW Myerson, LT Ferguson… - Advanced drug delivery …, 2020 - Elsevier
The bloodstream is the main transporting pathway for drug delivery systems (DDS) from the
site of administration to the intended site of action. In many cases, components of the …

DNA nanostructures and DNA‐functionalized nanoparticles for cancer theranostics

F Nicolson, A Ali, MF Kircher, S Pal - Advanced Science, 2020 - Wiley Online Library
In the last two decades, DNA has attracted significant attention toward the development of
materials at the nanoscale for emerging applications due to the unparalleled versatility and …

Approaches to improve EPR-based drug delivery for cancer therapy and diagnosis

MA Subhan, F Parveen, N Filipczak… - Journal of personalized …, 2023 - mdpi.com
The innovative development of nanomedicine has promised effective treatment options
compared to the standard therapeutics for cancer therapy. However, the efficiency of EPR …