Nutrients and bioactive compounds of Sorghum bicolor L. used to prepare functional foods: a review on the efficacy against different chronic disorders

W Khalid, A Ali, MS Arshad, F Afzal… - … Journal of Food …, 2022 - Taylor & Francis
Sorghum (Sorghum bicolor L.) is ranked five cereal crop worldwide. It belongs to the
Poaceae family and is formally part of plant-derived food. Nutritionally, it is composed of …

IgA and FcαRI: pathological roles and therapeutic opportunities

A Breedveld, M Van Egmond - Frontiers in immunology, 2019 - frontiersin.org
Immunoglobulin A (IgA) is the most abundant antibody class present at mucosal surfaces.
The production of IgA exceeds the production of all other antibodies combined, supporting …

TAK-101 nanoparticles induce gluten-specific tolerance in celiac disease: a randomized, double-blind, placebo-controlled study

CP Kelly, JA Murray, DA Leffler, DR Getts, AC Bledsoe… - Gastroenterology, 2021 - Elsevier
Background & aims In celiac disease (CeD), gluten induces immune activation, leading to
enteropathy. TAK-101, gluten protein (gliadin) encapsulated in negatively charged poly (dl …

Celiac disease: understanding the gluten-free diet

KA Bascuñán, MC Vespa, M Araya - European journal of nutrition, 2017 - Springer
Purpose The only effective and safe treatment of celiac disease (CD) continues being strict
exclusion of gluten for life, the so-called gluten-free diet (GFD). Although this treatment is …

Celiac disease and non-celiac gluten sensitivity

B Lebwohl, JF Ludvigsson, PHR Green - Bmj, 2015 - bmj.com
Celiac disease is a multisystem immune based disorder that is triggered by the ingestion of
gluten in genetically susceptible individuals. The prevalence of celiac disease has risen in …

Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction

SW Hong, PD Krueger, KC Osum, T Dileepan… - Nature, 2022 - nature.com
Gastrointestinal health depends on the adaptive immune system tolerating the foreign
proteins in food,. This tolerance is paradoxical because the immune system normally attacks …

Intestinal cell damage and systemic immune activation in individuals reporting sensitivity to wheat in the absence of coeliac disease

M Uhde, M Ajamian, G Caio, R De Giorgio, A Indart… - Gut, 2016 - gut.bmj.com
Objective Wheat gluten and related proteins can trigger an autoimmune enteropathy, known
as coeliac disease, in people with genetic susceptibility. However, some individuals …

[HTML][HTML] Sarcopenia in patients with colorectal cancer: A comprehensive review

O Vergara-Fernandez, M Trejo-Avila… - World journal of …, 2020 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most commonly diagnosed cancer globally and the
second cancer in terms of mortality. The prevalence of sarcopenia in patients with CRC …

[HTML][HTML] Celiac disease: From pathophysiology to treatment

I Parzanese, D Qehajaj, F Patrinicola… - World journal of …, 2017 - ncbi.nlm.nih.gov
Celiac disease, also known as “celiac sprue”, is a chronic inflammatory disorder of the small
intestine, produced by the ingestion of dietary gluten products in susceptible people. It is a …

Role of vitamin D in celiac disease and inflammatory bowel diseases

C Infantino, R Francavilla, A Vella, S Cenni, N Principi… - Nutrients, 2022 - mdpi.com
Vitamin D (VD) is a pro-hormone that has long been known as a key regulator of calcium
homeostasis and bone health in both children and adults. In recent years, studies have …