The utility of neurophysiological markers in the study of alcoholism
OBJECTIVE: This review attempts to differentiate neuroelectric measures (
electroencephalogram (EEG), event-related potentials (ERPs) and event-related oscillations …
electroencephalogram (EEG), event-related potentials (ERPs) and event-related oscillations …
Substance use disorders, externalizing psychopathology, and P300 event-related potential amplitude
We hypothesize the existence of an inherited predisposition for a spectrum of behaviors and
traits characterized by behavioral disinhibition. This externalizing spectrum includes …
traits characterized by behavioral disinhibition. This externalizing spectrum includes …
What is inherited in the predisposition toward alcoholism? A proposed model
H Begleiter, B Porjesz - Alcoholism: clinical and experimental …, 1999 - Wiley Online Library
Background: The etiological factors associated with the predisposition to develop alcohol
dependence remain largely unknown. In recent years, neurophysiological anomalies have …
dependence remain largely unknown. In recent years, neurophysiological anomalies have …
Genes mediate the association between P3 amplitude and externalizing disorders
Reduced P3 amplitude has been consistently linked to a spectrum of externalizing
disorders. Utilizing data from a large sample of adolescent male twins (N= 1196), we used …
disorders. Utilizing data from a large sample of adolescent male twins (N= 1196), we used …
The development of the N1 and N2 components in auditory oddball paradigms: a systematic review with narrative analysis and suggested normative values
Auditory event-related potentials (AERPs) are widely used in diverse fields of today's
neuroscience, concerning auditory processing, speech perception, language acquisition …
neuroscience, concerning auditory processing, speech perception, language acquisition …
The P300 event-related brain potential as a neurobiological endophenotype for substance use disorders: a meta-analytic investigation
AS Euser, LR Arends, BE Evans… - Neuroscience & …, 2012 - Elsevier
Endophenotypes are intermediate phenotypes on the putative causal pathway from
genotype to phenotype and can aid in discovering the genetic etiology of a disorder. There …
genotype to phenotype and can aid in discovering the genetic etiology of a disorder. There …
A Cholinergic Receptor Gene (CHRM2) Affects Event-related Oscillations
We report genetic linkage and association findings which implicate the gene encoding the
muscarinic acetylcholine receptor M2 (CHRM2) in the modulation of a scalp-recorded …
muscarinic acetylcholine receptor M2 (CHRM2) in the modulation of a scalp-recorded …
Direct and mediated associations between P300 amplitude in childhood and substance use disorders outcome in young adulthood
ME Habeych, PJ Charles, RJ Sclabassi, L Kirisci… - Biological …, 2005 - Elsevier
BACKGROUND: Attenuated amplitude of the P300 wave has been frequently documented
in youths at high risk for substance use disorders (SUDs). This investigation had two aims: 1) …
in youths at high risk for substance use disorders (SUDs). This investigation had two aims: 1) …
Auditory P300 event-related potentials and neurocognitive functions in opioid dependent men and their brothers
SM Singh, D Basu, A Kohli… - American Journal on …, 2009 - Taylor & Francis
Event-related-potentials (especially P300) and cognitive functioning as potential
endophenotypes have not been studied in opioid dependence. We compared auditory P300 …
endophenotypes have not been studied in opioid dependence. We compared auditory P300 …
Beyond the DSM: defining endophenotypes for genetic studies of substance abuse
JA Frederick, WG Iacono - Current Psychiatry Reports, 2006 - Springer
Although substance-related disorders are heritable, the genetic factors contributing to
vulnerability to these disorders are expected to be complex. Nonetheless, identifying genes …
vulnerability to these disorders are expected to be complex. Nonetheless, identifying genes …