Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms

K Huang, P Zhang, Z Zhang, JY Youn, C Wang… - Pharmacology & …, 2021 - Elsevier
COVID-19 has remained an uncontained, worldwide pandemic. While battling for the
disease in China, six Traditional Chinese Medicine (TCM) recipes have been shown to be …

The evolution and future of influenza pandemic preparedness

WN Harrington, CM Kackos, RJ Webby - Experimental & molecular …, 2021 - nature.com
The influenza virus is a global threat to human health causing unpredictable yet recurring
pandemics, the last four emerging over the course of a hundred years. As our knowledge of …

[HTML][HTML] Efficacy and safety of favipiravir, an oral RNA-dependent RNA polymerase inhibitor, in mild-to-moderate COVID-19: A randomized, comparative, open-label …

ZF Udwadia, P Singh, H Barkate, S Patil… - International Journal of …, 2021 - Elsevier
Objective To assess the efficacy and safety of favipiravir in adults with mild-to-moderate
coronavirus disease 2019 (COVID-19). Methods In this randomized, open-label, parallel …

A review on drug repurposing applicable to COVID-19

S Dotolo, A Marabotti, A Facchiano… - Briefings in …, 2021 - academic.oup.com
Drug repurposing involves the identification of new applications for existing drugs at a lower
cost and in a shorter time. There are different computational drug-repurposing strategies and …

A review of potential suggested drugs for coronavirus disease (COVID-19) treatment

P Tarighi, S Eftekhari, M Chizari, M Sabernavaei… - European Journal of …, 2021 - Elsevier
The latest pandemic, coronavirus disease-2019 (COVID-19), is associated with high
prevalence and easy transmission, which is expanding globally with no conventional …

[HTML][HTML] Role of machine learning techniques to tackle the COVID-19 crisis: systematic review

HB Syeda, M Syed, KW Sexton, S Syed… - JMIR medical …, 2021 - medinform.jmir.org
Background: SARS-CoV-2, the novel coronavirus responsible for COVID-19, has caused
havoc worldwide, with patients presenting a spectrum of complications that have pushed …

Combating oxidative stress and inflammation in COVID‐19 by molecular hydrogen therapy: mechanisms and perspectives

D Alwazeer, FFC Liu, XY Wu… - Oxidative Medicine and …, 2021 - Wiley Online Library
COVID‐19 is a widespread global pandemic with nearly 185 million confirmed cases and
about four million deaths. It is caused by an infection with the severe acute respiratory …

Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

An updated review of SARS-CoV-2 vaccines and the importance of effective vaccination programs in pandemic times

C García-Montero, O Fraile-Martínez, C Bravo… - Vaccines, 2021 - mdpi.com
Since the worldwide COVID-19 pandemic was declared a year ago, the search for vaccines
has become the top priority in order to restore normalcy after 2.5 million deaths worldwide …

Remdesivir metabolite GS-441524 effectively inhibits SARS-CoV-2 infection in mouse models

Y Li, L Cao, G Li, F Cong, Y Li, J Sun… - Journal of medicinal …, 2021 - ACS Publications
The outbreak of coronavirus disease 2019 (COVID-19) has resulted in a global pandemic
due to the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …