Malaria, in particular infection with P. falciparum (the most lethal of the human malaria
parasite species, responsible for nearly one million deaths every year), is one of the most …

Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …

Spirooxindoles occupy an important place in heterocyclic chemistry. Many natural
spirooxindole-containing compounds have been identified as bio-promising agents …

Malaria is among one of the most devastating and deadliest parasitic disease in the world
claiming millions of lives every year around the globe. It is a mosquito-borne infectious …

Nature products have been extensively used in the discovery and development of new
drugs, as the most important source of drugs. The triazole ring is one of main …

At present therapeutic options for severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) are very limited. We designed and synthesized three sets of small molecules using …

Viruses have been recognized as the etiological agents responsible for many pathological
conditions ranging from asymptomatic infections to serious diseases, even leading to death …

Click chemistry is perhaps the most powerful synthetic toolbox that can efficiently access the
molecular diversity and unique functions of complex natural products up to now. It enables …

Enlightened from our previous work of structural simplification of quinine and innovative
application of natural products against phytopathogenic fungi, lead structure 2, 8-bis …

Malaria, a nocuous disease, which has become a major challenge for the health resulting in
deaths of millions of people around the globe. Malaria is a parasitic disease propagated by …