Fragile X syndrome (FXS), the most common monogenic cause of intellectual disability and
autism spectrum disorder, has been one of the first neurodevelopmental disorders in which …

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition mainly
characterized by social impairments and repetitive behaviors. Among these core symptoms …

BACKGROUND FXLEARN, the first-ever large multisite trial of effects of disease-targeted
pharmacotherapy on learning, was designed to explore a paradigm for measuring effects of …

Autism spectrum disorder (ASD) has a multifactorial etiology. Major efforts are underway to
understand the neurobiological bases of ASD and to develop efficacious treatment …

Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although
cerebellar pathology has been observed in individuals with fragile X syndrome (FXS) and in …

Fragile X mental retardation protein (FMRP) binds a selected set of mRNAs and proteins to
guide neural circuit assembly and regulate synaptic plasticity. Loss of FMRP is responsible …

Fragile X syndrome (FXS), the most common inherited cause of intellectual disability and the
single-gene cause of autism, is caused by decreased expression of the fragile X messenger …

Multiple lines of evidence suggest that a deficiency of Fragile X Mental Retardation Protein
(FMRP) mediates dysfunction of the metabotropic glutamate receptor subtype 5 (mGluR5) in …

Dysfunction in the gene SCN2A, which encodes the voltage-gated sodium channel Nav1. 2,
is strongly associated with neurodevelopmental disorders including autism spectrum …

An edited volume that looks at the state of psychiatric genetics and how to chart a path
forward. In this edited collection, experts from psychiatric and statistical genetics …