Hexahydrocurcumin from Zingiberis rhizoma attenuates lipopolysaccharide-induced acute pneumonia through JAK1/STAT3 signaling pathway

R Li, Q Liang, Q Yang, W Dai, Y Xiao, H Pan, Z Zhang… - Phytomedicine, 2024 - Elsevier
Background Pneumonia is one of the major causes of death after pathogens infection.
Zingiberis rhizoma (GAN JIANG) is a herb that used in combination with other Chinese …

[HTML][HTML] Immunomodulatory effects of zinc and its impact on COVID-19 severity

M Dhawan, TB Emran, OP Choudhary - Annals of Medicine and Surgery, 2022 - Elsevier
The COVID-19 pandemic has led to severe financial, clinical, and societal repercussions
and imposed more pressure on the healthcare system of many nations. COVID-19 impacts …

Growth hormone-releasing hormone antagonist MIA-602 inhibits inflammation induced by SARS-CoV-2 spike protein and bacterial lipopolysaccharide synergism in …

G Granato, I Gesmundo, F Pedrolli, R Kasarla… - Frontiers in …, 2023 - frontiersin.org
COVID-19 is characterized by an excessive inflammatory response and macrophage
hyperactivation, leading, in severe cases, to alveolar epithelial injury and acute respiratory …

Increase in ischemia-modified albumin and pregnancy-associated plasma protein-A in COVID-19 patients

BG Sanchez, JM Gasalla, M Sánchez-Chapado… - Journal of Clinical …, 2021 - mdpi.com
This study was undertaken due to the urgent need to explore reliable biomarkers for early
SARS-CoV-2 infection. We performed a retrospective study analyzing the serum levels of the …

Th-1, Th-2, Th-9, Th-17, Th-22 type cytokine concentrations of critical COVID-19 patients after treatment with Remdesivir

K Kalantar, AG Talepoor, ME Vakili, N Karami, M Kalani… - Immunobiology, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the
world causing a pandemic known as coronavirus disease 2019 (COVID-19). Cytokine storm …

Corticosteroid Dosing Level, Incidence and Profile of Bacterial Blood Stream Infections in Hospitalized COVID-19 Patients

I Papic, P Bistrovic, T Cikara, N Busic, T Keres… - Viruses, 2024 - mdpi.com
COVID-19 patients with severe or critical symptoms are often treated with corticosteroids, per
contemporary guidelines. Due to their immunosuppressive and immunomodulatory …

Immune-inflammatory markers & clinical characteristics for outcomes in hospitalized SARS-CoV-2 infected patients of Pakistan: a retrospective analysis

A Khalid, RF Aqeel, A Nawaz, J Ahmad, ST Fatima… - …, 2023 - Taylor & Francis
Objective Accumulating evidence suggests the role of immune-inflammatory markers in
early risk stratification and prognostication of COVID-19 patients. We aimed to evaluate their …

Clinical predictors of COVID-19 mortality among patients in intensive care units: a retrospective study

A Al Mutair, A Al Mutairi, ARZ Zaidi, S Salih… - … journal of general …, 2021 - Taylor & Francis
Objective The ongoing pandemic of the coronavirus disease 2019 (COVID-19), which
originated from Wuhan, China, has been identified to be caused by the novel beta …

Nanomaterial-based methods for sepsis management

I Alipourfard, M Darvishi, F Ghazi, A Mobed - Enzyme and Microbial …, 2023 - Elsevier
Sepsis is a serious disease caused by an impaired host immune response to infection,
resulting in organ dysfunction, tissue damage and is responsible for high in-hospital …

Vascular function, systemic inflammation, and coagulation activation 18 months after COVID-19 infection: an observational cohort study

LH Willems, LMC Jacobs, LA Groh, H Ten Cate… - Journal of Clinical …, 2023 - mdpi.com
Introduction: Among its effect on virtually all other organs, COVID-19 affects the
cardiovascular system, potentially jeopardizing the cardiovascular health of millions …