Initial immune response after exposure to Mycobacterium tuberculosis or to SARS-COV-2: similarities and differences

A Aiello, S Najafi-Fard, D Goletti - Frontiers in Immunology, 2023 - frontiersin.org
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb) and Coronavirus disease-
2019 (COVID-19), whose etiologic agent is severe acute respiratory syndrome coronavirus …

Regulatory T cells (Tregs) and COVID-19: unveiling the mechanisms, and therapeutic potentialities with a special focus on long COVID

M Dhawan, AA Rabaan, S Alwarthan, M Alhajri… - Vaccines, 2023 - mdpi.com
The COVID-19 pandemic has caused havoc all around the world. The causative agent of
COVID-19 is the novel form of the coronavirus (CoV) named SARS-CoV-2, which results in …

The immunomodulatory role of cell-free approaches in SARS-coV-2-induced cytokine storm—A powerful therapeutic tool for COVID-19 patients

M Csobonyeiova, V Smolinska, S Harsanyi… - Biomedicines, 2023 - mdpi.com
Currently, there is still no effective and definitive cure for the coronavirus disease 2019
(COVID-19) caused by the infection of the novel highly contagious severe acute respiratory …

Adaptive immune dysfunction in patients with COVID-19 and impaired kidney function during the omicron surge

J Yan, J Wang, L Ding, S Liu, Y Zhan, J Lu, Z Li, L Gu… - Clinical …, 2023 - Elsevier
Background Little is known about the characteristics of lymphocyte subsets and the
association with patient outcomes in COVID-19 with and without impaired kidney function …

A Negative Regulatory Feedback Loop within the JAK–STAT Pathway Mediated by the Protein Tyrosine Phosphatase DUSP14 in Shrimp

M Luo, N Chen, D Han, B Hu, H Zuo… - The Journal of …, 2024 - journals.aai.org
The JAK–STAT pathway is a central communication node for various biological processes.
Its activation is characterized by phosphorylation and nuclear translocation of the …

Vascular dysfunction in hemorrhagic viral fevers: opportunities for organotypic modeling

E Zarate-Sanchez, SC George, ML Moya… - …, 2024 - iopscience.iop.org
The hemorrhagic fever viruses (HFVs) cause severe or fatal infections in humans. Named
after their common symptom hemorrhage, these viruses induce significant vascular …

Alterations in the CD56 and CD56+ T Cell Subsets during COVID-19

JD Vavilova, MO Ustiuzhanina, AA Boyko… - International Journal of …, 2023 - mdpi.com
The effectiveness of the antiviral immune response largely depends on the activation of
cytotoxic T cells. The heterogeneous group of functionally active T cells expressing the …

Enhanced Immunomodulatory Effects of Thymosin-Alpha-1 in Combination with Polyanionic Carbosilane Dendrimers against HCMV Infection

MS Espinar-Buitrago, E Magro-López… - International Journal of …, 2024 - mdpi.com
Resistance and toxicity associated with current treatments for human cytomegalovirus
(HCMV) infection highlight the need for alternatives and immunotherapy has emerged as a …

A Prospective Study Investigating Immune Checkpoint Molecule and CD39 Expression on Peripheral Blood Cells for the Prognostication of COVID-19 Severity and …

T Gambichler, J Rüth, S Goesmann, S Höxtermann… - Viruses, 2024 - mdpi.com
In patients with COVID-19, broad panels of immune checkpoint molecules (ICPMs) and the
purinergic signaling have not been studied in parallel. We aimed to perform in-depth …

K33 only mutant ubiquitin augments bone marrow‐derived dendritic cell‐mediated CTL priming via PI3K‐Akt pathway

YY Liang, XY Liao, JJ Jia, YZ Yin, YH Zhang… - …, 2024 - Wiley Online Library
To explore the effect of K33 only mutant ubiquitin (K33O) on bone marrow‐derived dendritic
cells'(BMDCs') maturity, antigen uptake capability, surface molecule expressions and BMDC …