Schizophrenia is a neurodevelopmental brain disorder whose genetic risk is associated with
shifting clinical phenomena across the life span. We investigated the convergence of …

Patients with schizophrenia have consistently shown brain volumetric abnormalities,
implicating both etiological and pathological processes. However, the genetic relationship …

Distinguishing between the effects of nature and nurture constitutes a major research goal
for those interested in understanding human development. It is known, for example, that …

The molecular organization of the human neocortex historically has been studied in the
context of its histological layers. However, emerging spatial transcriptomic technologies …

Response to survey questionnaires is vital for social and behavioural research, and most
analyses assume full and accurate response by participants. However, nonresponse is …

Importance Serious mental illnesses, including schizophrenia, bipolar disorder, and
depression, are heritable, highly multifactorial disorders and major causes of disability …

The purinergic pathway mediates both pro-inflammatory and anti-inflammatory responses,
whereas the breakdown of adenosine triphosphate (ATP) is in a critical equilibrium. Under …

Recent advances in genomics have revealed a wide spectrum of genetic variants
associated with neurodevelopmental disorders at an unprecedented scale. An increasing …

Abstract Background and Hypothesis Schizophrenia has been robustly associated with
multiple genetic and environmental risk factors. Childhood adversity is one of the most …

At mammalian neuronal synapses, synaptic vesicle (SV) glycoproteins are essential for
robust neurotransmission. Asparagine (N)-linked glycosylation is required for delivery of the …