Schizophrenia is a highly heritable psychiatric disorder characterized by widespread
functional and structural brain abnormalities. However, previous association studies …

The coronavirus SARS-CoV-2 invades the central nervous system, impacting the mental
health of COVID-19 patients. We performed a two-sample Mendelian randomization …

Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

Over the last years, the decreased costs and enhanced accessibility to large genome-wide
association studies datasets have laid the foundations for the development of polygenic risk …

Emerging research on neuroplasticity processes in psychosis spectrum illnesses—from the
synaptic to the macrocircuit levels—fill key gaps in our models of pathophysiology and open …

Objective: Schizophrenia is associated with increased risk of cardiovascular disease (CVD),
although there is variation in risk among individuals. There are indications of shared genetic …

Genome-wide association studies (GWAS) successfully identified multiple sclerosis (MS)
susceptibility variants. Despite this notable progress, understanding the biological context of …

Tandem repeat expansions (TREs) can cause neurological diseases but their impact in
schizophrenia is unclear. Here we analyzed genome sequences of adults with …

Recent postmortem transcriptomic studies of schizophrenia (SCZ) have shown hundreds of
differentially expressed genes. However, the extent to which these gene expression …

Schizophrenia is a polygenetic disease, the heterogeneity of which is likely complicated by
epigenetic modifications yet to be elucidated. Here, we performed transcriptomic analysis of …