Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Metabolic pathways integrate to support tissue homeostasis and to prompt changes in cell
phenotype. In particular, the heart consumes relatively large amounts of substrate not only to …

Exercise induces physiological cardiac growth and protects the heart against pathological
remodeling. Recent work suggests exercise also enhances the heart's capacity for repair …

Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …

Ageing is the biggest risk factor for cardiovascular disease. Cellular senescence, a process
driven in part by telomere shortening, has been implicated in age‐related tissue dysfunction …

The epidemic of heart failure has stimulated interest in understanding cardiac regeneration.
Evidence has been reported supporting regeneration via transplantation of multiple cell …

Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause
mortality, with increases in cardiorespiratory fitness associated with corresponding …

Regular physical activity with aerobic and muscle-strengthening training protects against the
occurrence and progression of cardiovascular disease and can improve cardiac function in …

The metabolic processes of endo-and exogenous compounds play an important role in
diagnosing and treating patients since many metabolites are laboratory biomarkers and/or …

Drawing on firsthand observations, Party and government documents, and survey data, this
study examines the causes and processes of the land for welfare policy in China. The …